Maya Sauthoff

ORCID: 0009-0004-1330-297X
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About
Contact & Profiles
Research Areas
  • Gut microbiota and health
  • Pediatric health and respiratory diseases
  • Asthma and respiratory diseases
  • Probiotics and Fermented Foods
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Microbial Community Ecology and Physiology
  • Bacteriophages and microbial interactions
  • Helicobacter pylori-related gastroenterology studies
  • IL-33, ST2, and ILC Pathways
  • Respiratory viral infections research
  • Mycobacterium research and diagnosis

Cornell University
2024

New York University
2020-2021

NYU Langone Health
2021

Pulmonary and Critical Care Associates
2020

SleepMed
2020

Rationale: Cross-sectional human data suggest that enrichment of oral anaerobic bacteria in the lung is associated with an increased T-helper cell type 17 (Th17) inflammatory phenotype.Objectives: In this study, we evaluated microbial and host immune-response dynamics after aspiration commensals using a preclinical mouse model.Methods: Aspiration mixture (MOC; Prevotella melaninogenica, Veillonella parvula, Streptococcus mitis) was modeled mice followed by variable time killing. The genetic...

10.1164/rccm.202005-1596oc article EN American Journal of Respiratory and Critical Care Medicine 2020-11-09

Background Microbiome studies of the lower airways based on bacterial 16S rRNA gene sequencing assess microbial community structure but can only infer functional characteristics. Microbial products, such as short-chain fatty acids (SCFAs), in have significant impact host's immune tone. Thus, approaches to analyses microbiome are necessary. Methods Here we used upper and airway samples from a research bronchoscopy smoker cohort. In addition, validated our results an experimental mouse model....

10.1183/13993003.03434-2020 article EN European Respiratory Journal 2021-01-14

Inter–microbial and host–microbial interactions are thought to be critical for the functioning of gut microbiome, but few tools available measure these interactions. Here, we report a method unbiased spatial sampling microbiome–host in at one micron resolution. This combines enzymatic situ polyadenylation both bacterial host RNA with RNA–sequencing. Application this mouse model intestinal neoplasia revealed biogeography microbiome as function location intestine, frequent strong...

10.1101/2024.11.18.624127 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-11-18
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