A5037457925- melanin and skin pigmentation
- Biochemical Analysis and Sensing Techniques
- Metal-Catalyzed Oxygenation Mechanisms
- Cyclopropane Reaction Mechanisms
- Skin Protection and Aging
- Computational Drug Discovery Methods
- Enzyme Catalysis and Immobilization
- Acne and Rosacea Treatments and Effects
- Metal complexes synthesis and properties
- Bioactive natural compounds
- Catalytic C–H Functionalization Methods
- Radical Photochemical Reactions
- Ferrocene Chemistry and Applications
- Bioactive Compounds and Antitumor Agents
- Click Chemistry and Applications
- Organic Chemistry Cycloaddition Reactions
- Metabolism and Genetic Disorders
- Neurological diseases and metabolism
- Olfactory and Sensory Function Studies
- Synthesis of Organic Compounds
Université Grenoble Alpes
2023-2024
Centre National de la Recherche Scientifique
2019-2024
Institut de Chimie Moléculaire et des Matériaux d'Orsay
2019-2022
Université Paris-Saclay
2019-2022
Université Paris-Sud
2019
Weatherford College
2019
Abstract In the context of developing ecofriendly chemistry, artificial enzymes are now considered as promising tools for synthesis. They prepared in particular with aim to catalyze reactions that rarely, if ever, catalyzed by natural enzymes. We discovered 1‐aminocyclopropane carboxylic acid oxidase reconstituted Cu II served an efficient Diels–Alderase. The kinetic parameters catalysis cycloaddition cyclopentadiene and 2‐azachalcone were determined ( K M =230 μ m , k app =3 h −1 ), which...
Melanogenesis inhibition constitutes a privileged therapeutic solution to treat skin hyperpigmentation, major dermatological concern associated with the overproduction of melanin by human tyrosinase (hsTYR). Despite existence many well-known TYR (tyrosinase) inhibitors commercialized in formulations, their hsTYR-inhibition efficacy remains poor since most them were investigated over mushroom (abTYR), model low homology relative hsTYR. Considering need for new potent hsTYR inhibitors, we...
Abstract In the context of developing ecofriendly chemistry, artificial enzymes are now considered as promising tools for synthesis. They prepared in particular with aim to catalyze reactions that rarely, if ever, catalyzed by natural enzymes. We discovered 1‐aminocyclopropane carboxylic acid oxidase reconstituted Cu II served an efficient Diels–Alderase. The kinetic parameters catalysis cycloaddition cyclopentadiene and 2‐azachalcone were determined ( K M =230 μ m , k app =3 h −1 ), which...
Melanogenesis inhibition constitutes a privileged therapeutic solution to treat skin hyperpigmentation, major dermatological concern associated with the overproduction of melanin by human tyrosinase (hsTYR). Despite existence many well-known TYR (tyrosinase) inhibitors commercialized in formulations, their hsTYR-inhibition efficacy remains poor since most them were investigated over mushroom (abTYR), model low homology relative hsTYR. Considering need for new potent hsTYR inhibitors, we...