- Cannabis and Cannabinoid Research
- Bacterial Infections and Vaccines
- Neuroscience and Neuropharmacology Research
- RNA regulation and disease
- Neuroinflammation and Neurodegeneration Mechanisms
- Pancreatic function and diabetes
- Biochemical effects in animals
- Autoimmune Neurological Disorders and Treatments
- Diet, Metabolism, and Disease
- T-cell and B-cell Immunology
- Barrier Structure and Function Studies
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
Colorado State University
2020-2024
Cannabidiol (CBD), the major non-psychoactive compound found in cannabis, is frequently used both as a nutraceutical and therapeutic. Despite anecdotal evidence an anticancer agent, little known about effect CBD has on cancer cells. Given intractability poor prognoses of brain cancers human veterinary medicine, we sought to characterize vitro cytotoxicity canine gliomas. Glioma cells treated with showed range from 4.9 8.2 μg/ml; appeared be more sensitive than human. Treatment >5...
The use of cannabidiol (CBD), the major non‐psychoactive compound derived from cannabis, as a nutraceutical in both human and veterinary medicine has increased steadily within past ten years despite lack scientific evidence for its effectiveness. Of cornucopia ailments that CBD supposedly treats, epilepsy, pain, cancer remain prominent areas interest to scientists general public. In world research, several publications have demonstrated is cytotoxic against breast, endometrial, glial, blood...
To evaluate whether cell-based and tissue-based immunofluorescent assays (IFAs) run in parallel could be used to detect glial fibrillary acidic protein (GFAP) autoantibodies the CSF of dogs with meningoencephalitis unknown origin (MUO) other CNS disorders.
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, is a chronic inflammatory disease. Although typically associated with inflammation of the lungs and other peripheral tissues, increasing evidence has uncovered neurological consequences attributable to Mtb infection. These include deficits in memory cognition, increased risk for neurodegenerative disease, progressive neuropathology. effects without CNS have been characterized, mechanism neurotoxicity unknown. We...