Liu Pai

ORCID: 0009-0004-4234-6023
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Escherichia coli research studies
  • Toxin Mechanisms and Immunotoxins
  • Antibiotics Pharmacokinetics and Efficacy
  • Bacterial biofilms and quorum sensing
  • Fungal Biology and Applications
  • Bacterial Identification and Susceptibility Testing
  • Monoclonal and Polyclonal Antibodies Research
  • Microbial Natural Products and Biosynthesis
  • Plant-Microbe Interactions and Immunity
  • Bacteriophages and microbial interactions

Shenzhen Children's Hospital
2023-2025

The rise of antibiotic-resistant pathogens has intensified the search for novel antimicrobial agents. This study aimed to isolate Streptomyces kanamyceticus from local soil samples and evaluate its properties, along with optimizing production bioactive compounds. Soil were collected regions, processed, analysed strains isolation using morphological characteristics molecular identification through 16S rRNA gene PCR assay. Antimicrobial activity was assessed against Escherichia coli,...

10.3389/fcimb.2024.1500440 article EN cc-by Frontiers in Cellular and Infection Microbiology 2025-01-06

Biofilms are a common survival strategy employed by bacteria in healthcare settings, which enhances their resistance to antimicrobial and biocidal agents making infections difficult treat. Mechanisms of biofilm-induced involve reduced penetration agents, increased expression efflux pumps, altered microbial physiology, genetic changes the bacterial population. Factors contributing formation biofilms include nutrient availability, temperature, pH, surface properties, interactions....

10.3389/fcimb.2023.1327069 article EN cc-by Frontiers in Cellular and Infection Microbiology 2023-12-19

Emergence of plasmid-born mobile colistin resistance (mcr) gene, a growing concern in healthcare. Therefore, this study aims to genomically characterize multidrug-resistant Escherichia coli and Klebsiella pneumoniae co-harboring the mcr-1 mcr-3 genes young children. E. (n=3) K. (n=2) were collected from abdominal secretion blood, respectively. The isolates screened using tryptone soya broth (TSB) with 4µl/ml polymyxin-B. Growing bacteria identified VITEK-2 system, MALDI-TOF 16s RNA...

10.1016/j.jgar.2023.07.012 article EN cc-by-nc-nd Journal of Global Antimicrobial Resistance 2023-07-20
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