- Non-Invasive Vital Sign Monitoring
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Hemodynamic Monitoring and Therapy
- Infrared Thermography in Medicine
- Long-Term Effects of COVID-19
- Cerebral Venous Sinus Thrombosis
- Heart Rate Variability and Autonomic Control
- Sleep and Work-Related Fatigue
- Sleep and related disorders
Karolinska Institutet
2019-2025
Introduction Aortic stiffness plays a critical role in the evolution of cardiovascular diseases, but assessment requires specialized equipment. Photoplethysmography (PPG) and single-lead electrocardiogram (ECG) are readily available healthcare wearable devices. We studied whether brief PPG registration, alone or combination with ECG, could be used to reliably estimate aortic stiffness. Methods A proof-of-concept study simultaneous high-resolution index finger recordings infrared PPG, blood...
Abstract Wearable technology, such as photoplethysmography (PPG), enables easily accessible individual health data with the potential for improved risk assessment. We hypothesized that overnight stiffness index (OSI), derived from nocturnal finger PPG, could be used to assess cardiovascular and vascular ageing. Subjects confirmed or suspected hypertension ( n = 79, 56 males) underwent simultaneous ambulatory blood pressure monitoring (ABPM) sleep polygraphy a continuous PPG registration....
Objective: Stiffness index (SI) derived from photoplethysmography (PPG) is a non-invasive method to estimate arterial stiffness. We investigated how overnight SI relates indices of stiffness ambulatory blood pressure monitoring (ABPM), (BP) levels, and cardiovascular risk. Design method: 79 individuals with confirmed or suspected hypertension (56 males, mean age 58 ± 11 years body mass 28.1 4.0 kg/m2; 28 smokers) performed simultaneous 24-hour ABPM (Spacelabs ABP monitors Ultralight) an...
Abstract Background Masked uncontrolled hypertension (MUCH) is defined as normal office blood pressure (BP) but elevated out-of-office BP in patients on antihypertensive treatment. MUCH associated with similar cardiovascular risk sustained and clinically challenging since this often remains undetected without measurements. Purpose To study the prevalence of following an acute coronary syndrome to utilise machine learning methods develop prediction models for identifying MUCH. Methods...
Aortic stiffness is an independent predictor of cardiovascular risk and plays important role for the development disease. However, it rarely measured in clinical practice as requires complicated methodology expensive equipment. We assessed whether high-resolution photoplethysmography (PPG) single-lead ECG, two methods available current consumer devices, could be used to measure aortic stiffness.Simultaneous recordings infrared PPG (earlobe index finger), single lead ECG (PowerLab,...
Studies show a link between short sleep duration and hypertension. The mechanistic associations blood pressure (BP) are less clear. We studied the association duration, pressure, metabolic profile as well obstructive apnoea in participants with suspected or confirmed hypertension undergoing 24 h ambulatory measurement (ABPM).We included 177 (mean age 57 ± 11 years, 67 women) referred for ABPM, available exact time-points bedtimes during recording. Daytime night-time BP values were calculated...
Objective: Studies have suggested an association between obstructive sleep apnea (OSA) and arterial stiffness. We aimed to further assess this relationship in hypertensive patients. Design method: In all, 199 patients with hypertension (mean age 57 ± 11 years, 73 females, body mass index 27.9 4.4 kg/m2, office blood pressure (BP) 147 19/89 mm Hg) referred for 24-h ambulatory monitoring (ABPM, recordings every 20 min throughout) underwent simultaneous over-night polygraphic recording (nasal...