A5100758088- Lattice Boltzmann Simulation Studies
- Blood properties and coagulation
- Rheology and Fluid Dynamics Studies
- Microfluidic and Bio-sensing Technologies
- Hydrocarbon exploration and reservoir analysis
- Platelet Disorders and Treatments
- Aerosol Filtration and Electrostatic Precipitation
- Evaluation and Optimization Models
- 2D Materials and Applications
- Chalcogenide Semiconductor Thin Films
- Synthesis and properties of polymers
- Radiative Heat Transfer Studies
- Industrial Technology and Control Systems
- Coal Properties and Utilization
- Fluid Dynamics and Turbulent Flows
- Fluid Dynamics and Thin Films
- Covalent Organic Framework Applications
- Nitric Oxide and Endothelin Effects
- Cellular Mechanics and Interactions
- Micro and Nano Robotics
- Geoscience and Mining Technology
- Adhesion, Friction, and Surface Interactions
- Phase-change materials and chalcogenides
- Membrane Separation and Gas Transport
- Heat and Mass Transfer in Porous Media
Queen Mary University of London
2013-2025
Guizhou Normal University
2024-2025
Zhengzhou University
2019-2024
China University of Geosciences (Beijing)
2021-2024
University College London
2012-2024
SOAS University of London
2024
Ningbo Institute of Industrial Technology
2024
Chinese Academy of Sciences
2015-2024
Jiangsu University
2024
Research Institute of Petroleum Exploration and Development
2020-2023
Asymmetric dimethylarginine is an endogenous inhibitor of NO synthesis that may mediate cardiovascular disease. Alanine-glyoxylate aminotransferase-2 (AGXT2) has been proposed to degrade asymmetric dimethylarginine. We investigated the significance AGXT2 in methylarginine metabolism vivo and examined effect this enzyme on blood pressure.In isolated mouse kidney mitochondria, we show deamination under physiological conditions. demonstrate increased dimethylarginine, reduced NO, hypertension...
We computationally study the transient motion of an initially spherical capsule flowing through a right-angled tube bifurcation, composed tubes having same diameter. The and deformation is simulated using three-dimensional immersed-boundary lattice Boltzmann method. modelled as liquid droplet enclosed by hyperelastic membrane following Skalak’s law (Skalak et al. , Biophys. J. vol. 13(3), 1973, pp. 245–264). fluids inside outside are assumed to have identical viscosity density. mainly focus...
We computationally study the motion of an initially spherical capsule flowing through a straight channel with orthogonal lateral branch, using three-dimensional immersed-boundary lattice-Boltzmann method. The is enclosed by strain-hardening membrane and contains internal fluid same viscosity as in which it suspended. Our primary focus to influence geometry side branch on path selection. Specifically, we consider case where cross-section half that various bifurcation configurations,...
Abstract Turbidites have been regarded as an important sedimentary infilling component in both oceans and lakes, but limited studies performed on the mechanisms governing initiation development of lacustrine turbidite systems. The present study offers unique insight into controls potential extent ancient systems by investigation Triassic Ordos Lake, where a large system had traced across >25 653 km 2 . This article shows comparison that Lake is larger than all known modern counterparts....
Cryogenic carbon capture (CCC) can preferentially desublimate $\text {CO}_2$ out of the flue gas. A widespread application CCC requires a comprehensive understanding desublimation properties. This is, however, highly challenging due to multiphysics behind it. study proposes lattice Boltzmann (LB) model on cooled cylinder surface during CCC. In two-dimensional (2-D) simulations, various and behaviours are produced in response different operation conditions, namely, gas velocity (Péclet number...
Background: Stroke-associated pneumonia (SAP) is associated with poor prognosis after acute ischemic stroke (AIS). Purpose: This study aimed to describe the parameters of coagulation function and evaluate association between fibrinogen-to-albumin ratio (FAR) SAP in patients AIS. Patients methods: A total 932 consecutive AIS were included. Coagulation measured at admission. All classified into two groups according optimal cutoff FAR point which sum specificity sensitivity was highest....
The aim of the present study was to investigate therapeutic effects pharmacological inhibition DDAH1 (dimethylarginine dimethylaminohydrolase 1), an enzyme that metabolizes endogenously produced nitric oxide synthase inhibitors, principally ADMA (asymmetric dimethylarginine). employs a series rodent models evaluate effectiveness DDAH1-selective inhibitor (L-257). Short-term involved development endotoxaemia using lipopolysaccharide and long-term intraperitoneal administration faecal slurry....
ObjectivesPrimary cilia are microtubule based organelles which control a variety of signalling pathways important in cartilage development, health and disease. This study examines the role intraflagellar transport (IFT) protein, IFT88, regulating fundamental actin organisation mechanics articular chondrocytes.MethodsThe used an established chondrocyte cell line with without hypomorphic mutation IFT88 (IFT88orpk). Confocal microscopy was to quantify F-actin myosin IIB organisation....
We propose a three-dimensional computational model to simulate the transient deformation of suspended cancer cells flowing through constricted microchannel. cell as liquid droplet enclosed by viscoelastic membrane, and its nucleus smaller stiffer capsule. The interaction with suspending fluid are solved well-tested immersed boundary lattice Boltzmann method. To identify minimal mechanical that can quantitatively predict in channel, we conduct extensive parametric studies effects rheology...
We study computationally the dynamics of oblate and prolate spheroidal capsules in simple shear flow with small inertia for a range dimensionless rates. The capsule is modelled as liquid droplet enclosed by hyperelastic membrane, its equatorial plane initially tilted out shear. find, at low rates, well-accepted tumbling motion not always stable both capsules. For an capsule, dominant modes increasing rate are follows: rolling staying shear, precessing following Jeffery's orbit [Proc. R. Soc....
How to prevent particle aggregation in the magnetic separation process is of great importance for high-purity separation, while it a challenging issue practice. In this work, we report novel method solve problem improving selectivity size-based by use gradient alternating field. The specially designed field capable dynamically adjusting direction without changing force acting on particles. Using direct numerical simulations, show that particles within certain center-to-center distance are...
Abstract
This work aims to expand the structure–property relationships of bromo-containing polyimides and influence bromine atoms on gas separation properties such materials. A series intrinsically microporous were synthesized from 2,2′-dibromo-4,4′,5,5′-bipohenyltetracarboxylic dianhydride (Br-BPDA) five bulky diamines, (7,7′-(mesitylmethylene)bis(8-methyldibenzo[b,e][1,4]dioxin-2-amine) (MMBMA), 7,7′-(Mesitylmethylene)bis(1,8-dimethyldibenzo[b,e][1,4] dioxin-2-amine) (MMBDA),...
Biomimetic enzyme loaded on porous organic polymers has used to develop mixed matrix membranes for efficient CO<sub>2</sub> capture.