A5113335649- Cardiac Imaging and Diagnostics
- Systemic Lupus Erythematosus Research
- Atherosclerosis and Cardiovascular Diseases
- Single-cell and spatial transcriptomics
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Cerebrovascular and Carotid Artery Diseases
- Cancer, Lipids, and Metabolism
- Lipoproteins and Cardiovascular Health
- Adipokines, Inflammation, and Metabolic Diseases
- Coronary Interventions and Diagnostics
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
National Medical Research Center of Cardiology
2021
Ministry of Health of the Russian Federation
2016
Relevance. Activation of innate and acquired immunity, accompanied by increased production classical (interleukin (IL) IL-1β, IL-6, tumor necrosis factor-α (TNF-α) interferon-γ (INF-γ)) proinflammatory cytokines in synovial fluid blood serum, plays an important role the pathogenesis rheumatoid arthritis (RA). Objective. To determine concentration TNF-α INF-γ RA patients advanced stage disease, to evaluate relationship between them, clinical indices disease activity, presence factor (RF),...
Background. Chronic autoimmune inflammation in arterial wall may lead to atherosclerosis progression. Objective. The aim of this study was investigate the association between Treg, Th17 and B1a cell blood frequencies as well IgM autoantibodies oxLDL abundance carotid atherosclerosis. Material methods. 18 patients with increased IMT (intima-media thickness) 65 different severity atherosclerotic plaques were included. assessed via direct immunofluorescence staining flow cytometry, measured...
Aim. Coronary stenting is the evidence-based treatment approach of stable angina. The objective was to determine incidence restenosis or atherosclerosis progression which led need for coronary angiography according a single center registry data. Materials and methods. procedure clinical data 3732 (2897 males) consecutive artery disease patients undergoing stenting, over five years between March 2010 September 2014, were subject this study. Over next 4 years, 1487 (1173 re-evaluated due...