Keegan A. Lorenz-Ochoa

ORCID: 0009-0004-6647-0141
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About
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Research Areas
  • Protein Structure and Dynamics
  • Spectroscopy and Quantum Chemical Studies
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Electronic and Structural Properties of Oxides
  • Protein purification and stability
  • Molecular Junctions and Nanostructures
  • CO2 Reduction Techniques and Catalysts
  • Electrochemical Analysis and Applications
  • Mass Spectrometry Techniques and Applications
  • RNA and protein synthesis mechanisms
  • Electrocatalysts for Energy Conversion
  • Surface and Thin Film Phenomena
  • RNA Research and Splicing
  • Viral Infectious Diseases and Gene Expression in Insects
  • Ion-surface interactions and analysis

The University of Texas at Austin
2023-2024

Cells achieve high spatiotemporal control over biochemical processes through compartmentalization to membrane-bound as well membraneless organelles that assemble by liquid-liquid phase separation. Characterizing the balance of forces within these environments is essential understanding their stability and function, water an integral part condensate, playing important role in mediating electrostatic hydrogen-bonding interactions. Here, we investigate ultrafast, picosecond hydrogen-bond...

10.1021/jacs.3c10862 article EN Journal of the American Chemical Society 2023-12-07

Water often serves as both a reactant and solvent in electrocatalytic reactions. Interfacial water networks can affect the transport kinetics of these reactions, e.g., hydrogen evolution reaction CO2 reduction reaction. Adding cosolvents that influence hydrogen-bonding (H-bonding) environment, such dimethyl sulfoxide (DMSO), has potential to tune reactivity important reactions by regulating interfacial local environment network. We investigate H-bonding water-DMSO cosolvent mixtures on gold...

10.1021/acs.jpclett.4c00645 article EN The Journal of Physical Chemistry Letters 2024-04-15

Biomolecular condensates provide a mechanism for compartmentalization of biomolecules in eukaryotic cells. These liquid-like are formed via liquid–liquid phase separation, by plethora interactions, and can mediate several biological processes healthy Expansions dipeptide repeat proteins, DPRs, which arginine rich DPRs like poly-proline-arginine (PR), poly-glycine-arginine (GR), partition RNA into however induce cell toxicity. Here, we use (GR)20 as model poly-GR condense it using either...

10.1021/jacs.4c11226 article EN Journal of the American Chemical Society 2024-11-26

Cells achieve high spatiotemporal control over biochemical processes through compartmentalization to membrane-bound, as well membraneless organelles that assemble by liquid-liquid phase separation. Characterizing the balance of forces within these environments is essential understanding their stability and function, water an integral part condensate, playing a nontrivial role in mediating electrostatic hydrogen bonding interactions. Here we investigate picosecond hydrogen-bond dynamics model...

10.26434/chemrxiv-2023-6ml88 preprint EN cc-by-nc 2023-08-10

Water often serves as both the reactant and solvent in electrocatalytic reactions. The interfacial water network can affect transport kinetics of these reactions, e.g., hydrogen evolution reaction CO2 reduction reaction. Adding cosolvents that influence bonding environment, such DMSO, has potential to tune reactivity important reactions through regulation local environment network. We investigate networks DMSO cosolvent mixtures on gold surfaces using a combination surface enhanced infrared...

10.26434/chemrxiv-2023-9x6ht preprint EN cc-by-nc-nd 2023-10-26
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