A5011194800- Fluid Dynamics and Vibration Analysis
- Lattice Boltzmann Simulation Studies
- Fluid Dynamics and Turbulent Flows
- Model Reduction and Neural Networks
- Elasticity and Material Modeling
- Blood properties and coagulation
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Aerosol Filtration and Electrostatic Precipitation
- Cardiac Arrhythmias and Treatments
- Aerodynamics and Acoustics in Jet Flows
- Blood Coagulation and Thrombosis Mechanisms
- Platelet Disorders and Treatments
- Cardiac Valve Diseases and Treatments
- Hemoglobin structure and function
- Coronary Interventions and Diagnostics
Universidad Carlos III de Madrid
2023-2025
Cranfield University
2019
Clot formation is a crucial process that prevents bleeding, but can lead to severe disorders when imbalanced. This regulated by the coagulation cascade, biochemical network controls enzyme thrombin, which converts soluble fibrinogen into fibrin fibers constitute clots. Coagulation cascade models are typically complex and involve dozens of partial differential equations (PDEs) representing various chemical species’ transport, reaction kinetics, diffusion. Solving these PDE systems...
Stroke is a leading cause of death and disability worldwide. Atrial myopathy, including fibrosis, associated with an increased risk ischaemic stroke, but the mechanisms underlying this association are poorly understood. Fibrosis modifies myocardial structure, impairing electrical propagation tissue biomechanics, creating stagnant flow regions where clots could form. can be mapped non-invasively using late gadolinium enhancement magnetic resonance imaging (LGE-MRI). However, fibrosis maps not...
Stroke is a leading cause of death and disability worldwide. Atrial myopathy, including fibrosis, associated with an increased risk ischemic stroke, but the mechanisms underlying this association are poorly understood. Fibrosis modifies myocardial structure, impairing electrical propagation tissue biomechanics, creating stagnant flow regions where clots could form. can be mapped non-invasively using late gadolinium enhancement magnetic resonance imaging (LGE-MRI). However, fibrosis maps not...
Abstract Atrial fibrillation (AF) disrupts the circulation of blood through left atrium (LA), and may result in relative stasis atrial appendage (LAA), increasing thromboembolic risk. Anticoagulant agents can lower this risk, but currently used target common pathway central to coagulation cascade, bleeding Anticoagulants such as factor XI/XII inhibitors initial phase intrinsic pathway, with a significantly associated However, these agents’ efficacy preventing thrombosis patient-specific flow...
Clot formation is a crucial process that prevents bleeding, but can lead to severe disorders when imbalanced. This regulated by the coagulation cascade, biochemical network controls enzyme thrombin, which converts soluble fibrinogen into fibrin fibers constitute clots. Coagulation cascade models are typically complex and involve dozens of partial differential equations (PDEs) representing various chemical species' transport, reaction kinetics, diffusion. Solving these PDE systems...
Abstract Intraventricular vector flow mapping (VFM) is a growingly adopted echocardiographic modality that derives time-resolved two-dimensional maps in the left ventricle (LV) from color-Doppler sequences. Current VFM models rely on kinematic constraints arising planar incompressibility. However, these are not informed by crucial information about physics; most notably pressure and shear forces within fluid resulting accelerations. This limitation has rendered unable to combine different...
We present an efficient implementation for running three-dimensional numerical simulations of fluid-structure interaction problems on single GPUs, based Nvidia CUDA through Numba and Python. The incompressible flow around moving bodies is solved in this framework the Immersed Boundary Method tailored GPU, where different GPU grid architectures are exploited to optimize overall performance. By targeting a single-GPU, we avoid GPU-CPU GPU-GPU communication bottlenecks, since all simulation...
We present an efficient implementation for running three-dimensional numerical simulations of fluid-structure interaction problems on single GPUs, based Nvidia CUDA through Numba and Python.The incompressible flow around moving bodies is solved in this framework the Immersed Boundary Method tailored GPU, where different GPU grid architectures are exploited to optimize overall performance.By targeting a single-GPU, we avoid GPU-CPU GPU-GPU communication bottlenecks, since all simulation data...
The unsteady flow fields generated by convoluted aero engine intakes are major sources of instabilities that can compromise the performance downstream turbomachinery components.This highlights need for high spatial and temporal resolution measurements will allow a greater understanding aerodynamics but also improvements in our current predictive capability such complex flows.This paper presents validation modern Lattice Boltzmann method (LBM) to predict swirl distortion characteristics...