A5007390209- Circadian rhythm and melatonin
- Neuroendocrine regulation and behavior
- Radiomics and Machine Learning in Medical Imaging
- Neuroscience and Neuropharmacology Research
- DNA and Nucleic Acid Chemistry
- Memory and Neural Mechanisms
- Regulation of Appetite and Obesity
- Neural dynamics and brain function
- Sleep and Wakefulness Research
Friedrich-Alexander-Universität Erlangen-Nürnberg
2021-2024
Abstract Innate behaviors meet multiple needs adaptively and in a serial order, suggesting the existence of hitherto elusive brain dynamics that brings together representations upcoming during their selection. Here we show behavioral transitions, possible are encoded by specific signatures neuronal populations lateral hypothalamus (LH) active near beta oscillation peaks. Optogenetic recruitment intrahypothalamic inhibition at this phase eliminates transitions. We transitions elicited...
Neural circuits supporting innate behaviors, such as feeding, exploration, and social interaction, intermingle in the lateral hypothalamus (LH). Although previous studies have shown that individual LH neurons change their firing relative to baseline during one or more rate dynamics of populations within behavioral episodes well coordination behavior-related remain largely unknown. Here, using unsupervised graph-based clustering freely behaving male mice, we identified distinct cells whose...
Abstract Hippocampal pyramidal cells encode an animal’s location by single action potentials and complex spike bursts. These elementary signals are believed to play distinct roles in memory consolidation. The timing of spikes bursts is determined intrinsic excitability theta oscillations (5–10 Hz). Yet contributions these dynamics place fields remain elusive due the lack methods for specific modification burst discharge. In mice lacking Kcnq3-containing M-type K + channels, we find that cell...