A5045499397- Heme Oxygenase-1 and Carbon Monoxide
- Inflammasome and immune disorders
- Gout, Hyperuricemia, Uric Acid
- Reproductive tract infections research
- Eicosanoids and Hypertension Pharmacology
- Atherosclerosis and Cardiovascular Diseases
- Adipose Tissue and Metabolism
- Galectins and Cancer Biology
- Cancer, Hypoxia, and Metabolism
- Lipid metabolism and disorders
- Helicobacter pylori-related gastroenterology studies
- Peroxisome Proliferator-Activated Receptors
- Cancer, Lipids, and Metabolism
- Biomarkers in Disease Mechanisms
- Balance, Gait, and Falls Prevention
- Infectious Aortic and Vascular Conditions
- Aortic Disease and Treatment Approaches
- Inflammatory mediators and NSAID effects
- Renal and Vascular Pathologies
- Cytomegalovirus and herpesvirus research
- Cardiac Ischemia and Reperfusion
- Heart Failure Treatment and Management
- High Altitude and Hypoxia
- Ginseng Biological Effects and Applications
- Aortic aneurysm repair treatments
Guiyang Medical University
2014-2025
Affiliated Hospital of Guizhou Medical University
2015-2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2021
Nanyang Medical College
2004-2011
Army Medical University
2006
Xinqiao Hospital
2006
Sheng Jing Hospital
2004-2005
Atherosclerosis (AS) is a chronic inflammatory disease involving cell death and responses. Pyroptosis, newly discovered pro-inflammatory programmed process, exacerbates However, the roles of cathepsin B (CTSB) in pyroptosis AS remain unclear. To gain further insight, we fed ApoE -/- mice high-fat diet to investigate effects mechanisms CTSB overexpression silencing on AS. We also explored specific role vascular smooth muscle cells (VSMCs) vitro . The study revealed that led formation plaques,...
The aim of this study was to investigate the expression characteristics and interrelationships FNDC5 pyroptosis-associated molecules in peripheral blood mononuclear cells patients with coronary heart disease (CHD). Patients were divided into stable angina (SA), unstable (UA), acute myocardial infarction (AMI) groups based on different clinical symptoms. According Gensini score, they then mild, moderate, severe lesion groups. control (NC) group also set. ELISA assay employed detect levels...
In this study,
Atherosclerosis is a chronic inflammatory disease. Pyroptosis triggers and amplifies the response plays an important role in atherosclerosis. Cathepsin B (CTSB) can promote atherosclerosis activate NOD-like receptor protein 3 (NLRP3) to mediate pyroptosis. Dapagliflozin (DAPA) inhibit cell pyroptosis improve This study aimed explore effect of DAPA on oxidized low-density lipoprotein (ox-LDL)-induced vascular smooth muscle cells (VSMCs) its underlying mechanism.We investigate ox-LDL-induced...
This study attempted to observe the role of fibronectin type III domain-containing protein 5 (FNDC5) in atherosclerosis development and underlying mechanism.After being fed a high-fat diet (HFD), ApoE-/- mice were injected with saline, control adenovirus (Ad-vector), or FNDC5 overexpressing (Ad-FNDC5). chow considered control. After 12 weeks treatment, levels serum high-density lipoprotein cholesterol (HDL-C), total (TC), low-density (LDL-C), triglyceride (TG), irisin detected by commercial...
Background There are no long-term (>10 years) follow-up evaluations of the effects handstand exercise or studies on use equipment for passive exercise. Objective To report a 40-year investigation Chinese man who has been practicing 40 years. Design This observational was conducted in Guizhou Province, China. Participant A (currently) 66-year-old had years followed up. Interventions Physical and auxiliary examinations were carried out to determine human body. Main Measures The...
Abstract Background AT1 receptor gene ( AGTR1 ) is related to essential hypertension (EH), and left ventricular hypertrophy (LVH) arterial stiffness are common complications of EH. This study aimed explore the association between genotype LVH in EH patients. Methods A total 179 patients were recruited this study. Oral exfoliated cells collected from each patient, genetic polymorphism (rs4524238) was assessed using a sequencing platform. The outcomes stiffness. Results Among patients, 114...