A5076000650- Medical Imaging Techniques and Applications
- Recycling and utilization of industrial and municipal waste in materials production
- Radiopharmaceutical Chemistry and Applications
- Concrete and Cement Materials Research
- Peptidase Inhibition and Analysis
- Radiomics and Machine Learning in Medical Imaging
- Anesthesia and Neurotoxicity Research
- Protease and Inhibitor Mechanisms
- Neuropeptides and Animal Physiology
- Material Selection and Properties
- Prostate Cancer Treatment and Research
- Radiation Therapy and Dosimetry
- AI in cancer detection
- Cardiac Structural Anomalies and Repair
- Nuclear materials and radiation effects
Renji Hospital
2022-2024
Shanghai Jiao Tong University
2022-2024
Shanghai University of Medicine and Health Sciences
2022-2024
Jiading District Central Hospital
2024
University of Shanghai for Science and Technology
2024
68Ga-labeled fibroblast activation protein inhibitors, such as [68Ga]Ga-DOTA-FAPI-04 and [68Ga]Ga-DOTA-FAPI-46, have been successfully applied in positron emission tomography imaging of various tumor types. To broaden the PET tracers different nuclides for studies FAP-dependent diseases, we herein report radiosynthesis preclinical evaluation two 11C-labeled FAP 11C-RJ1101 11C-RJ1102. Two phenolic hydroxyl precursors based on a quinoline amide core coupled with 2-cyanopyrrolidine moiety were...