Nilanchala Sahu

ORCID: 0009-0005-0768-9888
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Research Areas
  • Computational Drug Discovery Methods
  • Synthesis and biological activity
  • Synthesis and Characterization of Heterocyclic Compounds
  • Drug Solubulity and Delivery Systems
  • Synthesis of heterocyclic compounds
  • Berberine and alkaloids research
  • Phytochemistry and biological activities of Ficus species
  • Synthesis and Reactions of Organic Compounds
  • Ocular Surface and Contact Lens
  • Dermatology and Skin Diseases
  • Microbial Natural Products and Biosynthesis
  • Complementary and Alternative Medicine Studies
  • Natural Antidiabetic Agents Studies
  • Cholinesterase and Neurodegenerative Diseases
  • Synthesis of Organic Compounds
  • Cancer Mechanisms and Therapy
  • Plant biochemistry and biosynthesis
  • Retinal Diseases and Treatments
  • Nonlinear Optical Materials Research
  • Advancements in Transdermal Drug Delivery
  • Psoriasis: Treatment and Pathogenesis
  • Synthesis of β-Lactam Compounds

Sharda University
2024

Amity University
2023

Dr. Hari Singh Gour University
2012

The goal of this investigation is to improve the topical delivery medicine by preparing and maximizing potential a nanotransferosome gel infused with Solanum xanthocarpum methanolic extract (SXE) provide localized regulated distribution. Thin-film hydration was used create SXE-infused nanotransferosomes (SXE-NTFs), Box–Behnken design them. Phospholipon 90G (X1), cholesterol (X2) sodium cholate (X3) were chosen as independent variables, their effects on vesicle size (Y1), polydispersity index...

10.3390/gels10020119 article EN cc-by Gels 2024-02-02

Solanum xanthocarpum (SX) has been used to treat a variety of diseases, including skin disorders like psoriasis (PSO). SX possesses many pharmacological activities anti-inflammatory, anti-cancer, immunosuppressive, and healing qualities. However, the multi-target mechanism on PSO still needs clarity. Materials methods: The Indian Medicinal Plants, Phytochemicals Therapeutics (IMPPAT) database Swiss Target Prediction online tool were find active phytochemical components their associated...

10.1016/j.jsps.2023.101788 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2023-09-16

(1) Background: Diabetic retinopathy (DR) is a major complication of diabetes, marked by abnormal angiogenesis, microaneurysms, and retinal hemorrhages. Traditional Ayurvedic medicine advocates multi-target strategies for DR management. However, the mechanisms which Solanum xanthocarpum (SX) Plumbago zeylanica (PZ) exert therapeutic effects are not well understood; (2) Methods: To investigate these mechanisms, we employed network pharmacology molecular docking techniques. Phytochemicals from...

10.3390/biology13090732 article EN cc-by Biology 2024-09-18

<title>Abstract</title> Psoriasis (PSO) is a chronic immune-mediated skin condition characterized by abnormal keratinocyte growth and inflammation. Clinical occurrences have hinted to potential connection between fungi psoriasis as several Malassezia species Candida Albicans been linked distinct subtypes. Triazoles Antifungal drugs used mainly treat Fungal diseases. In this study, we intend find out different target mechanism pathway through which triazoles can act in the pathophysiology of...

10.21203/rs.3.rs-3990527/v1 preprint EN cc-by Research Square (Research Square) 2024-03-14

Rutin and berberine are naturally occurring polyphenols but their usefulness is restricted by low bioavailability poor solubility. Thus, delivering rutin–berberine in the form of niosomes simultaneously hoped to enhance permeability through nasal route for treatment depression. Thin-film hydration approach was used generate dual drug-loaded (rutin–berberine) encapsulating rutin berberine. Various analytical techniques were characterize morphology, size, compatibility, leakage particles....

10.1080/01932691.2024.2425951 article EN Journal of Dispersion Science and Technology 2024-11-12
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