- Cardiac Health and Mental Health
- Heart Failure Treatment and Management
- Cardiovascular Health and Risk Factors
- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- Heart Rate Variability and Autonomic Control
- Cardiovascular and exercise physiology
- Antibiotic Use and Resistance
- Health and Lifestyle Studies
- Urinary Tract Infections Management
- Mindfulness and Compassion Interventions
- Cardiac Arrest and Resuscitation
- Dialysis and Renal Disease Management
- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Stuttering Research and Treatment
University of Kentucky
2023-2025
Bhaktapur Cancer Hospital
2023-2024
The social determinants of health (SDOH) have been recognized as an important contributor to individual's status. A valid and reliable instrument is needed for researchers clinicians measure SDOH. However, there considerable variability in the screening methodologies, well a lack standardization definitions methods capturing reporting SDOH data both electronic record software vendors national experts on Protocol Responding Assessing Patient Assets, Risks, Experiences (PRAPARE) commonly used...
Abstract Background: Depressive symptoms, anxiety, and inadequate social support are predictors of health-related quality life (HRQoL) in persons with heart failure, but the prediction HRQoL is multifaceted, mechanisms underlying association unknown. Self-care maintenance may moderate associations among these predictors, which essential to better failure outcomes. Objectives: To determine whether self-care moderates direct indirect effects on through psychological status (i.e., depressive...
Background Health-related quality of life (HRQoL) is poor in patients with heart failure. Psychological (ie, depressive symptoms [DS], anxiety, and perceived control) physical functional status) factors are associated HRQoL. The dynamic relationships among these variables their impact on HRQoL remain unclear, limiting the ability to design effective interventions. Purpose Our aim was evaluate a moderated mediation model, which association between control hypothesized be mediated by DS...
Clinicians and researchers often assume that symptom burden is associated with self-care management (SCM) in patients heart failure (HF). However, association not borne out simple regression analyses may be because another variable mediates the association. Fatalism an appropriate candidate for mediation belief circumstances are predetermined without opportunity control by individuals.
Abstract Objectives Data on antimicrobial resistance (AMR) among children in Nepal are limited. Here we have characterized the causes of bacterial bloodstream infections (BSIs), patterns and mechanisms β-lactamase production Enterobacterales attending outpatient inpatient departments a secondary care paediatric hospital Nepal. Methods We retrospectively collected demographic clinical data culture-proven BSIs between January 2017 December 2022 <18 years 50-bedded hospital. Stored...
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Physical activity (PA) is essential following an acute cardiac event. Cardiac rehabilitation (CR) commonly prescribed, and PA after CR recommended. Because of age-related changes in functional ability multi-comorbidity, many older patients struggle to continue performing at home CR. Depressive symptoms anxiety are prevalent associated with poor self-care, including lack daily PA. Yoga has been demonstrated improve psychological physical health outcomes patients, but it unknown whether yoga,...
Background: Patients with heart failure (HF) frequently experience poor sleep quality and multiple HF symptoms, both of which are linked to diminished functional status. Poor can manifest as prolonged latency, short duration, low efficiency, or difficulty staying asleep. symptoms encompass different dimensions: presence, frequency, severity, distress symptoms. Different dimensions may uniquely influence status, necessitating tailored interventions, yet how individual impact status remains...
Background: Disparities in coronary heart disease (CHD) and other chronic related conditions, such as poor sleep quality psychological distress, have been observed rural areas. Both conditions can negatively affect progression, possibly through their impact on physical activity. The relationships, however, among quality, activity depressed CHD patients not examined. Purpose: purpose of this study was to determine the association (i.e., fragmentation [frequent interruption] nocturnal/sleep...
Background: Black patients with heart failure (HF) have a higher physical and psychological distress which disproportionately worsens their health quality of life (QOL) than those from other racial/ethnic groups. less commonly receive optimal therapy for HF white patients, can result in poorer functional status. report levels depressive symptoms. Higher symptoms further worsen status lower QOL. Hypothesis: We hypothesized that would predict QOL this relationship be mediated by Methods: Using...
Background: Heart failure (HF) is not a homogeneous condition, and comorbidities, such as renal dysfunction, commonly complicate the clinical picture. However, differences in patient-centered outcomes (PCO), depressive symptoms, health-related quality of life, functional status, adherence, self-care behaviors, have been explored patients with HF without dysfunction. Hypothesis: We hypothesized that there significant difference PCO between diagnosed heart dysfunction those Methods: A...
Transferrable mechanisms of quinolone resistance (TMQR) can lead to fluoroquinolone non-susceptibility in addition chromosomal mechanisms. Some evidence suggests that is increasing among the pediatric population. We sought determine occurrence TMQR genes quinolone-resistant E. coli and K. pneumoniae causing urinary tract infections Nepalese outpatient children (< 18 years) identify molecular characteristics TMQR-harboring isolates.We performed antimicrobial susceptibility testing, phenotypic...
Introduction: Depressive symptoms, anxiety, and inadequate social support are predictors of quality life (QOL) in patients with heart failure (HF), but prediction QOL is multifaceted mechanisms underlying association unknown. Essential to better HF outcomes, self-care maintenance (SCM) may moderate associations among these predictors. The interplay depressive support, SCM their influence on remains uncertain. Purpose: To determine whether (1) symptoms anxiety mediate the QOL, (2) moderates...