- Streptococcal Infections and Treatments
- Biochemical and Structural Characterization
- Congenital Heart Disease Studies
- Ammonia Synthesis and Nitrogen Reduction
- Machine Learning in Bioinformatics
- Cardiac Valve Diseases and Treatments
- Nanomaterials for catalytic reactions
- Bacterial Infections and Vaccines
- Polysaccharides and Plant Cell Walls
- Cardiovascular and Diving-Related Complications
- Enzyme Structure and Function
- Pharmacological Effects of Natural Compounds
- Protein Structure and Dynamics
- Vascular anomalies and interventions
- Plant Stress Responses and Tolerance
- Redox biology and oxidative stress
- Cardiac Arrhythmias and Treatments
- Bacterial Genetics and Biotechnology
- RNA and protein synthesis mechanisms
- Cardiac Structural Anomalies and Repair
- vaccines and immunoinformatics approaches
- Fungal and yeast genetics research
- Antimicrobial Resistance in Staphylococcus
- Neonatal and Maternal Infections
- Tuberculosis Research and Epidemiology
Jagiellonian University
2020-2024
Uniwersytecki Szpital Dziecięcy
2023-2024
Warsaw University of Technology
2022
University of Warsaw
2016
University of St Andrews
2014-2015
Vlaams Instituut voor Biotechnologie
2013
Vrije Universiteit Brussel
2013
The cell wall emerged as one of the important structures in plant stress responses. To investigate effect cold on properties, content and localization pectins pectin methylesterase (PME) activity, were studied two maize inbred lines characterized by different sensitivity to cold. Low temperature (14/12 °C) caused a reduction PME activity leaves chilling-sensitive line, especially after prolonged treatment (28 h 7 days). Furthermore, immunocytohistological studies, using JIM5 JIM7 antibodies,...
To cause disease and persist in a host, pathogenic commensal microbes must adhere to tissues. Colonization infection depend on specific molecular interactions at the host-microbe interface that involve microbial surface proteins, or adhesins. date, adhesins are only known bind host receptors non-covalently. Here we show streptococcal protein SfbI mediates covalent interaction with fibrinogen using an unusual internal thioester bond as ‘chemical harpoon’. This cross-linking reaction allows...
NrdH-redoxins are small reductases with a high amino acid sequence similarity glutaredoxins and mycoredoxins but thioredoxin-like activity. They function as the electron donor for class Ib ribonucleotide reductases, which convert ribonucleotides into deoxyribonucleotides. We solved x-ray structure of oxidized NrdH-redoxin from Corynebacterium glutamicum (Cg) at 1.5 Å resolution. Based on this monomeric structure, we built homology model Mycobacterium tuberculosis (Mt). Both have typical...
We report the first-stage percutaneous palliation in a newborn with rare heterotaxy syndrome variant including interrupted inferior vena cava, partial anomalous pulmonary venous drainage, and restrictive interatrial communication. Virtual reality imaging aided visualisation, decision-making, planning. Successful atrial septoplasty performed via internal jugular vein was followed by stenting of ductus arteriosus.
Recently, catalysts with hydrotalcites and hydrotalcite-derived compounds have attracted particular interest due to their specific properties, mostly well-developed texture, high thermal stability, favorable acid–base properties. In this work, we report the investigation of ammonia synthesis on barium-promoted cobalt supported Mg-Al mixed oxides different Mg/Al molar ratios. The obtained were characterized using TGA-MS, nitrogen physisorption, XRPD, TEM, STEM-EDX, H2-TPD, CO2-TPD, tested in...
Gram-positive pathogens are a major concern to global health, with increasing resistance antimicrobials and the lack of preventative therapeutics. Understanding how these bacteria interact host cells is vital for development novel strategies combat disease. One most crucial steps in infection adhesion cell. The discovery complex cell-surface associated proteins, such as pili, has advanced our knowledge this interaction, however precise molecular mechanisms underlying process remain unclear....