A5042740858- Cancer Immunotherapy and Biomarkers
- Urban and spatial planning
- Ferroptosis and cancer prognosis
- Lymphoma Diagnosis and Treatment
- Immune cells in cancer
- Immune Cell Function and Interaction
- Cell Adhesion Molecules Research
- Urbanization and City Planning
- interferon and immune responses
- Cytokine Signaling Pathways and Interactions
- Immunotherapy and Immune Responses
- Cancer Genomics and Diagnostics
- Financial Crisis of the 21st Century
- T-cell and B-cell Immunology
- Hemoglobin structure and function
- Atherosclerosis and Cardiovascular Diseases
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Diagnosis and Treatment
- Methemoglobinemia and Tumor Lysis Syndrome
- Urban Planning and Landscape Design
- Chronic Lymphocytic Leukemia Research
- Metabolomics and Mass Spectrometry Studies
- Cancer Diagnosis and Treatment
- Korean Urban and Social Studies
- Radiopharmaceutical Chemistry and Applications
Fujitsu (Japan)
2024-2025
Tokyo National Hospital
2024
National Cancer Center
2024
National Cancer Center Hospital East
2023
Tokyo University of Science
1995-2016
United Nations
2003-2005
Nikki-Universal (Japan)
2001
Meiji (Japan)
1989
Building Research Institute
1983-1987
Ministry of Housing and Urban-Rural Development
1983-1986
The five-year survival rate of lung-cancer patients with left-sided N2 non-small-cell disease is worse than that for those right-sided lesions and this partly caused by inadequate nodal dissection due to anatomical limitations. To overcome the problem performing in left mediastinum, several modifications operative technique have been tried past 18 years. rates treated each procedure were retrospectively compared study. method mediastinal nodes was modified at three periods (1973-1980,...
Resistance to immune checkpoint blockade remains challenging in patients with non-small cell lung cancer (NSCLC). Tumor-infiltrating leukocyte (TIL) quantity, composition, and activation status profoundly influence responsiveness immunotherapy. This study examined the landscape NSCLC tumor microenvironment by analyzing TIL profiles of 281 fresh resected tissues. Unsupervised clustering based on numbers percentages 30 types classified adenocarcinoma (LUAD) squamous carcinoma (LUSQ) into cold,...
Three years from now in 2019, we will celebrate the 100th year of Japan’s City Planning Act (“Old Act,” 1919). The Old was Japanese positive response to western modern planning, which developed Europe and north America late 19th early 20th centuries gradually spreading all over world. Japan first nation East Asia systematically responded this process (Watanabe 1993) and, after establishing system homeland, spread it turn neighboring countries regions imperial expansion. This “dual spread” is...
本稿は、日本語「まちづくり」の定義の論理構造の解明にむけられています。まず予備作業として、用語の定義に関する論理的議論をおこないます。ついで、都市計画・建築系の4人のまちづくり論者の言説による「まちづくり定義」の論理分析をおこない。それらは、西山夘三、田村明、佐藤滋、澤村明の4氏（6例）です。その結果をうけて、これら多様な「まちづくり定義」を体系的に整理する方法として、定義語に「次元」と「広義・狭義」の概念を導入することによる仮説枠組を提起してむずびとします。
Abstract Purpose Visualizing mitochondria in cancer cells from human pathological specimens may improve our understanding of biology. However, using immunohistochemistry to evaluate remains difficult because almost all contain and the number per cell have important effects on mitochondrial function. Herein, we established an objective system (Mito-score) for evaluating machine-based processing hue, saturation, value color spaces. Methods The Mito-score was defined as COX4 (mitochondrial...
In undertaking the restoration from Hanshin-Awaji earthquake, administrative body of Hyogo prefecture decided to introduce a new method called "Two Step Planning Determination". Yet, this dose not necessarily seem have been carried out smoothly in actual recovery process and what was attempted study find some issues by analyzing real situation areas where readjustment project had under way. From analysis, following could be pointed out. First, because first step planning determination made...
On 4 November 2015, Dr Yorifusa Ishida, Professor Emeritus of Tokyo Metropolitan University, died from pneumonia in at the age 83. As a pioneer Japanese planning history, he was long-...
1936年、台湾総督府は内地日本の旧都市計画法（1919：以下、旧法）を母法とした台湾都市計画令を立案した。共通する都市計画技術を基本構造とする旧法と台湾都市計画令を比較することを通して、台湾都市計画令の特徴及び台北市での運用・実施段階での成果を分析することは、日本の都市計画史研究上も大きな意義がある。本研究では、当時内地で発行された資料や現地での調査を基に、第 6次市区計画及び台湾都市計画令を旧法との相違点、その背景・意図等の視点で比較し、台湾都市計画令の特徴を明らかにしている。それらは、 (1) 旧法上の議論を踏まえた制度的先進性、 (2) 伝統・風土の考慮を背景とする特殊性、 (3) 植民地統治による私権の制限を背景とする特殊性にまとめられる。また、内地では郊外地の整備が後追い的になったのに対して、台湾では先行的にコントロールできた点は、内地の失敗の克服という点で最も際立った特徴である。
近年、社区営造（まちづくり）が展開されている台湾においては、まちづくりの人材育成・活動支援システムが整備されつつある。 2002年に台湾全土に８つ設立された「社区営造センター」は、リーダーとなる住民を育成しながら社区（コミュニティー）のまちづくり活動の支援を行う公設民営の新しいシステムである。 2003年には、新たに「県市社造センター」が各県市に設置され始め、「社造センター」は台湾全土に急速に広まっている。本研究では、まず、台湾におけるまちづくりの歴史的展開を整理する。そして、「社造センター」の事例を通して、台湾におけるまちづくりの人材育成・活動支援システムの特徴及び課題を明らかにすることを目的とする。その上で日本のまちづくりへの示唆を行う。日本においてもまちづくりの人材育成・活動支援のあり方は重要な課題であり、相互にまちづくりの経験を学ぶ観点からも意義がある。
This is part of a historical study Capital Reconstruction Program, 1923-28, which was carried out after the Great Kanto Earthquake. article tries to analyze and evaluate role played in planning process by Charles A. Beard, noted American historian, political scientist municipal reformer, who visited Japan before earthquake. The author concludes Beard’s first visit success but second failure because his approach heavily biased modern urban planning, had little relevancy Japanese situation at...
Planning scholars and practitioners who are making a master plan, much interested in how to harmonize the relationship between municipal-wide general public interests individual citizen's requests. We believe it is important secure bottom-up system that would allow incorporate citizen proposals into plan. Based upon logical structure model for we analyzed plan-making stage of Komae City's Master Plan. found were incorporated plan by changing some elements its structure. Leading factors...
Professor Yorifusa Ishida (1932-2015), who was an IPHS council member, one of the leading scholars in research field city planning post-war Japan. His interest expands so widely to include system, history, land readjustment, building line, use controls and planning, development profit, rural citizen participation. He has publicized his findings, practical proposals, academic political views many books, articles papers. It is rather unfortunate, however, that most them are published Japanese...
都市計画技術の中核に存する「マスタープラン」は、個別のプランや計画決定をコントロールする規範として機能しています。わが国都市計画制度は、下位計画が上位計画へ「適合」することを義務づけることによって、多数のプランが相互に「適合関係」で結ばれた「プラン体系」を規定しています。このような「プランの適合関係」は、マスタープランを真に主導力をもつものとするためには、決定的に重要な論点となっています。本論文の前半では、「プランの適合関係」をめぐって、都市計画法令等における「適合」関係の用語分析をおこない、同法が規定するプラン体系における適合関係を総体的に明らかにします。ついで後半では、これをうけて「プランの適合関係」に関する一般的・理論的な考察を試論として展開します。最後に、それに基づいて、現状のマスタープランのあり方を批判し、また新たな研究課題を提起して結びとします。
<p>Percentage of PD-1+ CD8 T+ and PD-L1+ cells in respective immune subtypes. (a, b) Data were presented as a percentage (a) (b) per indicated CD8+ T cell subset LUAD LUSQ. % naïve CD8; or total cells. CM EM EMRA ns; not significant. * p<0.05. **P<0.01.</p>
<p>Percentage of PD-1+ CD8 T+ and PD-L1+ cells in respective immune subtypes. (a, b) Data were presented as a percentage (a) (b) per indicated CD8+ T cell subset LUAD LUSQ. % naïve CD8; or total cells. CM EM EMRA ns; not significant. * p<0.05. **P<0.01.</p>