A5100701023- Metabolomics and Mass Spectrometry Studies
- Traditional Chinese Medicine Studies
- Sepsis Diagnosis and Treatment
- Chronic Kidney Disease and Diabetes
- Genetic Associations and Epidemiology
- Genetic Syndromes and Imprinting
- Gout, Hyperuricemia, Uric Acid
- Dialysis and Renal Disease Management
- Diet and metabolism studies
- Potassium and Related Disorders
- Metabolism and Genetic Disorders
- Pharmacological Effects of Natural Compounds
- Advanced Chemical Sensor Technologies
- Respiratory Support and Mechanisms
- Computational Drug Discovery Methods
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ginseng Biological Effects and Applications
- Heme Oxygenase-1 and Carbon Monoxide
- Acute Kidney Injury Research
- Gut microbiota and health
- Heart Failure Treatment and Management
- Traditional Chinese Medicine Analysis
- Oral microbiology and periodontitis research
- Cancer-related molecular mechanisms research
- Thermal Regulation in Medicine
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2024
Tianjin University of Traditional Chinese Medicine
2004-2024
Heilongjiang University of Chinese Medicine
2015-2016
Harbin University
2015-2016
First Affiliated Hospital of Heilongjiang University of Chinese Medicine
2015-2016
Tianjin University
2007
At present, safe and effective treatment drugs are urgently needed for diabetic kidney disease (DKD). Circulating protein biomarkers with causal genetic evidence represent promising drug targets, which provides an opportunity to identify new therapeutic targets. Summary data from two quantitative trait loci studies presented, one involving 4,907 plasma proteins 35,559 individuals the other encompassing 4,657 among 7,213 European Americans. statistics DKD were obtained a large genome-wide...
Early diagnosis of Alzheimer's disease (AD) is an attractive strategy to increase the survival rate patients.
Background In recent years, the role of gut microbiota and derived metabolites in renal disease has attracted more attention. It been established that is a potential target for medical interventions including chronic kidney (CKD), acute injury (AKI) calculus. Emerging evidence related dialysis treatment to microbial composition function intestines, there are many reports HD, but few studies have PD. Previous found PD patients intestinal flora disturbances, so we speculate its may be...
A nontargeted metabolomics approach was developed to examine metabolic differences in serum samples from the mild cognitive impairment and Alzheimer's disease subjects.
Severe sepsis (SS) remains among the leading causes of death in both developed and developing countries.
Hyperuricemia (HUA), a condition characterized by elevated levels of uric acid (UA) in the bloodstream, is intricately connected to an imbalance gut microbiota. UA, byproduct purine metabolism, serves as crucial endogenous antioxidant. Recent research indicates that modifying microbiome offers promising avenue for managing HUA. This work delves into complex relationship between HUA and changes microbiota, examining its impact on UA excretion, reabsorption, activity enzymes involved...
Urinary UPLC-MS metabolomics could dissect the underlying mechanisms of HXC protects against SS.
Non-targeted mass spectrometry was used to characterize peripheral biomarkers associated with the urine metabolome in severe sepsis (SS) patients. This is an efficient and convenient tool for diagnosing screening of SS a high-risk population.
Cholangiocarcinoma (CC) accounts for approximately 25% of all hepatobiliary malignancies, including intra- and extrahepatic cholangiocarcinoma (ICC ECC) has a high mortality rate. The clinical manifestations liver function tests the ICC ECC diseases are too similar to distinguish between them. Diagnosis remains difficult because lack sensitive diagnostic tests, although MRI CT with endoscopic ultrasound provide useful information in certain patients, but invasive, time-consuming or...
Sepsis is a commonly encountered scenario in an intensive care unit (ICU), and the kidney one of organs frequently affected.
Sepsis-induced acute lung injury (ALI) remains a leading cause of death in intensive care units and early detection is very important. This work showed that metabolite phenotype profiling might be useful tool for the effective diagnosis further understanding ALI.
The aim of this study was to use lipidomics identify lipid molecules that could predict patients with sepsis-induced lung injury.
<p dir="ltr"><a href="" target="_blank">At present, safe and effective treatment drugs are urgently needed for diabetic kidney disease (DKD). Circulating protein biomarkers with causal genetic evidence represent promising drug targets, which provides an opportunity to identify new therapeutic targets. Summary data from two quantitative trait loci (pQTL) studies: one involving 4,907 plasma proteins 35,559 individuals, the other encompassing 4,657 among 7,213 European Americans....
<p dir="ltr"><a href="" target="_blank">At present, safe and effective treatment drugs are urgently needed for diabetic kidney disease (DKD). Circulating protein biomarkers with causal genetic evidence represent promising drug targets, which provides an opportunity to identify new therapeutic targets. Summary data from two quantitative trait loci (pQTL) studies: one involving 4,907 plasma proteins 35,559 individuals, the other encompassing 4,657 among 7,213 European Americans....
Network pharmacology was employed to probe into the mechanism of Fushen Granules in treating peritoneal dialysis-rela-ted peritonitis(PDRP) rats. The main active components were searched against Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform, their targets predicted. PDRP-related retrieved from DisGeNET other databases. common shared by drug disease identified online tool, protein-protein interaction(PPI) network targets. obtained 276 imported DAVID for GO...