- Colorectal Cancer Surgical Treatments
- Abdominal Surgery and Complications
- Cardiac Arrest and Resuscitation
- Wound Healing and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Burn Injury Management and Outcomes
- Mechanical Circulatory Support Devices
- Venous Thromboembolism Diagnosis and Management
- Intestinal and Peritoneal Adhesions
- Enhanced Recovery After Surgery
Erasmus MC
2015-2024
Maasstad Ziekenhuis
2023
Erasmus University Rotterdam
2023
Anastomotic leakage after gastrointestinal surgery remains a challenging clinical problem. This study aimed to investigate the effectiveness of TissuCol (fibrin glue), Histoacryl Flex (n-butyl-2-cyanoacrylate), and Duraseal (polyethylene glycol) on colorectal anastomotic healing during experimental colitis.We first performed colectomy 7 days 10 mg trinitrobenzene sulfonic acid (TNBS)-induced colitis validate rat TNBS-colitis-colectomy model. Subsequently, this model was used in 73 Wistar...
Introduction. Perioperative bowel perfusion (local hemodynamic index [LHI]) was measured with a miniaturized dynamic light scattering (mDLS) device, aiming to determine whether anastomotic correlates the healing process and LHI measurement assists in detection of leakage (AL) colorectal surgery. Methods. A partial colectomy performed 21 male Wistar rats. Colonic LHIs were recorded during operation. On postoperative day (POD) 3, rats examined for AL manifestations. Anastomotic before...