A5059029185- Kidney Stones and Urolithiasis Treatments
- Urological Disorders and Treatments
- Infectious Aortic and Vascular Conditions
- Ureteral procedures and complications
- Tissue Engineering and Regenerative Medicine
- ZnO doping and properties
- Nanoplatforms for cancer theranostics
- Hemostasis and retained surgical items
Chinese Academy of Sciences
2022-2024
University of Science and Technology of China
2022
Ureteral stents are commonly utilized as a medical device to aid the flow of urine. However, biofilm formation and encrustation complications have been clinical problems. To overcome this challenge, heparin/poly-L-lysine-copper (Hep/PLL-Cu) nanoparticle was immobilized on dopamine-coated polyurethane surface (PU/NPs). The stability structural properties nanoparticles were characterized by Zeta potential, poly dispersion index, transmission electron microscopy, atom force microscopy contact...
In this work, an investigation on the Zn-Cu alloy coated with heparin was conducted in order to explore potentiality of its application as a feasible alternative for biodegradable implants, specific goal addressing issue encrustation urinary system. The stability nanoparticles were characterized by dynamic light scattering. Typical surface characterization such X-ray photoelectron spectroscopy, scanning electron microscopy, and atomic force microscopy used demonstrate successful...
Polyurethane (PU) ureteral stents are used in clinics to maintain the patency. Due biofilm formation and encrustation complications, long-term clinical usage has been limited. It is therefore necessary develop an effective response this unmet medical need. A heparin/poly-l-lysine/copper (NPs) coating was developed our previous work that showed effect of preventing infection vitro. In work, a further study conducted by grafting NPs on then were implanted into infectious bladders Wistar rats...
Introduction: Ureteral stents blocked with encrustation are a common clinical complication and affect bacteria colonization inflammatory response. In this study, different concentrations of copper (0.25, 0.5, 1, 1.5, 2 g/L) were immobilized on polyurethane (PU) that showed functionalization microbe resistance regulation the inflammation response to RAW264.7. Methods: X-ray photoelectron spectroscopy (XPS), atomic force microscope (AFM) static water contact angles used analyze surface...