A5103098591- Cancer-related molecular mechanisms research
- Advanced Technologies in Various Fields
- Protein Structure and Dynamics
- Genomics and Phylogenetic Studies
- Educational Technology and Pedagogy
- Technology Assessment and Management
- AI and Big Data Applications
- Enzyme Structure and Function
Shandong University
2023
Recent studies have highlighted the critical roles of long non-coding RNAs (lncRNAs) in various biological processes, including but not limited to dosage compensation, epigenetic regulation, cell cycle and differentiation regulation. Consequently, lncRNAs emerged as a central focus genetic studies. The identification subcellular localization is essential for gaining insights into crucial information about lncRNA interaction partners, post- or co-transcriptional regulatory modifications,...
Abstract Protein structure modeling is an important but challenging task. Recent breakthroughs in Cryo-EM technology have led to rapid accumulation of density maps, which facilitate scientists determine protein structures it remains time-consuming. Fortunately, artificial intelligence has great potential automating this process. In study, we present SMARTFold, a deep learning prediction model combining sequence alignment features and map features. First, using map, sample representative...