A5093131506- Radical Photochemical Reactions
- Catalytic C–H Functionalization Methods
- Oxidative Organic Chemistry Reactions
- Sulfur-Based Synthesis Techniques
- Advanced Photocatalysis Techniques
- Synthesis and Catalytic Reactions
University of California, San Diego
2023-2024
University of Michigan
2023
Herein, we demonstrate 1) that Lewis base heteroatom coordination to diaryliodonium salts is not required for light-driven radical generation and 2) radicals generated by this route can be captured transition-metals coupling reactions. These results are the first step toward developing new aryl reactions without exogenous photocatalysts.
We demonstrate 1) that halogen bonding is not critical for enabling light-driven radical generation from diaryliodonium salts and 2) radi-cals generated by this route can be captured transition-metals C–H arylation reactions. These results are the first step toward devel-oping new metal-catalyzed aryl couplings without exogenous photocatalysts.
We demonstrate (1) detectable halogen bonding is not critical for enabling light-driven radical generation from diaryliodonium salts and (2) radicals generated by this route can be captured transition-metals C-H arylation reactions. These results are the first step toward developing new metal-catalyzed aryl couplings without exogenous photocatalysts.
We report a modular photoredox strategy for the synthesis of aryl vinyl sulfoximines from sulfinamide and halide starting materials. This demonstrates difunctionalization sulfinamides to sulfoximine products with excellent configurational retention stereoselective trans alkenes. Under mild redox conditions, we propose generation nitrogen centered radical that is resonance stabilized by sulfur partner, increasing overall lifetime. disclose thus well suited capture, leading products. process...
Diaryliodonium salts are bench stable aryl radical precursors. While photocatalysts generally responsible for generation, recent reports have emerged exhibiting photocatalyst-free generation using select Lewis bases as activators. Herein, we demonstrate 1) the ability of numerous to enable light-driven and 2) these radicals can be captured by transition-metals coupling reactions. These results first step toward developing new organometallic reactions without photocatalysts.
While photocatalysts are generally responsible for radical generation from bench stable diaryliodonium salts, recent reports have emerged exhibiting photocatalyst-free using select Lewis bases as activators. Herein, we demonstrate 1) the ability of numerous to enable light-driven and 2) these radicals can be captured by transition-metals coupling reactions. These results first step toward developing new organometallic aryl reactions without photocatalysts.