A5020765660- BRCA gene mutations in cancer
- Gynecological conditions and treatments
- HER2/EGFR in Cancer Research
- Advanced Breast Cancer Therapies
- Cancer Risks and Factors
- Ectopic Pregnancy Diagnosis and Management
- Reproductive Biology and Fertility
- Breast Cancer Treatment Studies
- Cancer Genomics and Diagnostics
- Reproductive Health and Contraception
University of Padua
2024
Istituto Oncologico Veneto
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2024
Hospital Universitario Son Espases
2024
Hospital Universitario Son Dureta
2008
Abstract Background Breast cancer (BC) in women aged ≤40 years carrying germline pathogenetic variants (PVs) BRCA1/2 genes is infrequent but often associated with aggressive features. Human epidermal growth factor receptor 2 (HER2)‐low‐expressing BC has recently emerged as a novel therapeutic target not been characterized this rare patient subset. Methods Women newly diagnosed early‐stage HER2‐negative (HER2‐0 and HER2‐low) PVs from 78 health care centers worldwide were retrospectively...