A5081634448- Systemic Lupus Erythematosus Research
- Acute Myeloid Leukemia Research
- Rheumatoid Arthritis Research and Therapies
- Pregnancy and Medication Impact
- T-cell and B-cell Immunology
- Blood disorders and treatments
- Reproductive System and Pregnancy
- Immunodeficiency and Autoimmune Disorders
University of Amsterdam
2014
Amsterdam UMC Location University of Amsterdam
2014
<h3>Objective</h3> Previous work has suggested that the granulocyte macrophage colony stimulating factor (GM-CSF)–GM-CSF receptor α axis (GM-CSFRα) may provide a new therapeutic target for treatment of rheumatoid arthritis (RA). Therefore, we investigated cellular expression GM-CSFRα in RA synovial tissue and effects anti-GM-CSFRα antibody vitro vivo preclinical model RA. <h3>Methods</h3> We compared on macrophages positive CD68 or CD163 biopsy samples from patients with psoriatic (PsA) to...
X-linked moesin-associated immunodeficiency (X-MAID) is a recently identified combined caused by mutation in the moesin (