A5019608003- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Advanced Proteomics Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Microbial Metabolic Engineering and Bioproduction
- Advanced Chemical Sensor Technologies
Molecular Discovery (United Kingdom)
2017-2024
To date, the main limitations for LC-MS-based untargeted lipidomics reside in lack of adequate computational and cheminformatics tools that are able to support analysis several thousands species from biological samples, enabling data mining automating lipid identification external prediction processes. address these issues, we developed Lipostar, novel vendor-neutral high-throughput software effectively supports both targeted LC-MS lipidomics, implementing acquisition, user-friendly...
Mass Spectrometry Imaging (MSI) is an established and powerful MS technique that enables molecular mapping of tissues cells finding widespread applications in academic, medical, pharmaceutical industries. As both the MSI technology have undergone rapid growth improvement, challenges associated with analyzing large datasets identifying many detected species become apparent. The lack readily available comprehensive software covering all necessary data analysis steps has further compounded this...
Lipids are structurally diverse molecules that play a pivotal role in plethora of biological processes. However, deciphering the roles specific lipids is challenging due to existence numerous isomers. This high chemical complexity lipidome one major challenges lipidomics research, as traditional liquid chromatography-mass spectrometry (LC-MS) based approaches often not powerful enough resolve these isomeric and isobaric nuances within complex samples. Thus, uniquely suited benefits provided...
Untargeted metabolomics is a growing field, in which recent advances high-resolution mass spectrometry coupled with liquid chromatography (LC-MS) have facilitated untargeted approaches as result of improvements sensitivity, accuracy, and resolving power. However, very large amount data are generated. Consequently, using computational tools now mandatory for the in-depth analysis data. This article describes MetAbolomics ReSearch (MARS), an all-in-one vendor-agnostic graphical user...