A5035636864- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Adrenal and Paraganglionic Tumors
- Esophageal Cancer Research and Treatment
- Genital Health and Disease
- Renal and Vascular Pathologies
- Renal and related cancers
- Multiple and Secondary Primary Cancers
- Pituitary Gland Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Screening and Detection
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Surgical Treatments
- Ureteral procedures and complications
- Economic and Financial Impacts of Cancer
- Palliative Care and End-of-Life Issues
- Organ Donation and Transplantation
- Cardiac tumors and thrombi
- Cutaneous Melanoma Detection and Management
- Cardiac and Coronary Surgery Techniques
Université de Montréal
2022-2025
McGill University Health Centre
2024
Objective: To test whether the contemporary robot-assisted nephroureterectomy (RNU) is associated with more favorable in-hospital outcomes than historical RNU, relative to same endpoints in open NU (ONU).
ABSTRACT Purpose To quantify improvements in adverse in‐hospital outcomes between historical and contemporary robot‐assisted radical cystectomy (RARC) versus open RC (ORC). Material Methods Within the National Inpatient Sample (2010–2019), RARC ORC ileal conduit diversion patients were identified. Multivariable logistic Poisson regression models fitted. Results Of patients, 1343 (39%) (2010–2014) 2087 (61%) (2015–2019). 5812 (54%) 5019 (46%) contemporary. Versus counterparts, exhibited...
Objective To address cancer‐specific mortality free‐survival (CSM‐FS) differences in patients with urothelial carcinoma of the urinary bladder (UCUB) vs non‐UCUB who underwent trimodal therapy (TMT), according to organ confined (OC: T2N0M0) non‐organ (NOC: T3–4NanyM0 or TanyN1–3M0) clinical stages. Patients and Methods Within Surveillance, Epidemiology, End Results database (2004–2020), we identified cT2–T4N0–N3M0 cancer treated TMT, defined as combination transurethral resection tumour,...
Abstract Background In-hospital mortality and complication rates after partial radical nephrectomy in patients with history of heart-valve replacement are unknown. Patients Methods Relying on the National Inpatient Sample (2000–2019), kidney cancer undergoing or were stratified according to presence absence replacement. Multivariable logistic Poisson regression models addressed adverse hospital outcomes. Results Overall, 39,673 underwent versus 94,890 nephrectomy. Of those, 248 (0.6%) 676...
PurposeTo assess in-hospital mortality and complication rates after radical cystectomy (RC) in patients with history of heart-valve replacement.Materials methodsUsing the National Inpatient Sample (2000–2019), non-metastatic bladder cancer undergoing RC were stratified according to replacement. Regression models (RM) predicted hospital outcomes.ResultsOf 25,535 patients, 250 (1.0%) harbored Heart-valve replacement older (median 74 vs. 70 years), more frequently male (87.2 80.6%), had...
Abstract Objective The aim of this study was to test for the association between paraplegia and perioperative complications as well in-hospital mortality after radical cystectomy (RC) non-metastatic bladder cancer. Methods Perioperative were tabulated in RC patients with or without National Inpatient Sample (2000–2019). Results Of 25,527 patients, 185 (0.7%) paraplegic. Paraplegic younger (≤70 years age; 75 vs. 53%), more frequently female (28 19%), harbored Charlson Comorbidity Index ≥3 (56...
Abstract The overall survival (OS) improvement after the advent of several novel systemic therapies, designed for treatment metastatic urothelial carcinoma urinary bladder (mUCUB), is not conclusively studied in either contemporary UCUB patients and/or non‐UCUB patients. Within Surveillance, Epidemiology, and End Results database, (2017–2020) historical (2000–2016) therapy‐exposed and, subsequently, were identified. Separate Kaplan–Meier multivariable Cox regression (CRM) analyses first...
Abstract Objective To test whether race/ethnicity affects stage or grade distribution at upper tract urothelial carcinoma (UTUC) diagnosis. Methods Within the Surveillance, Epidemiology, and End Results (SEER) database 2004–2020, UTUC patients were identified. Multivariable logistic regression models tested for association between as well diagnosis according to renal pelvis vs. ureteral origin. Stage presentation was defined (i) metastatic (T any N M 1 ) (ii) advanced (locoregional 3-4 0-2...
Radical prostatectomy (RP) may be a treatment option for prostate cancer in patients with chronic kidney disease (CKD). However, the effect of CKD on adverse in-hospital outcomes after RP is not well known. Descriptive analyses, propensity score matching (PSM), and multivariable logistic Poisson regression models were used to address National Inpatient Sample between 2005 2019. severity was stratified as mild (stage I/II) versus moderate III) severe IV/V). Of 191 050 patients, 4349 (2.3%)...
To assess cancer-specific mortality (CSM) and other-cause (OCM) rates in patients with rare histological prostate cancer subtypes.
Background: Trimodal therapy is considered the most validated bladder-sparing treatment in patients with organ-confined urothelial carcinoma of urinary bladder (T2N0M0). However, scarce evidence exists regarding cancer-specific mortality (CSM) differences between trimodal and other non-extirpative multimodal options such as radiotherapy alone after transurethral resection (TURBT + RT) or chemotherapy CT). Methods: Within Surveillance, Epidemiology, End Results database (2004–2020), we...
Abstract Background In incidental prostate cancer (IPCa), elevated other‐cause mortality (OCM) may obviate the need for active treatment. We tested OCM rates in IPCa according to treatment type and grade we hypothesized that is significantly higher not‐actively‐treated patients. Methods Within Surveillance, Epidemiology, End Results database (2004−2015), patients were identified. Smoothed cumulative incidence plots as well multivariable competing risks regression models fitted address after...
In metastatic urethral cancer, temporal trends, and patterns of inpatient palliative care (IPC) use are unknown.