Benjamin Knez

ORCID: 0009-0006-4879-8818
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About
Contact & Profiles
Research Areas
  • Microfluidic and Capillary Electrophoresis Applications
  • Protein purification and stability
  • Monoclonal and Polyclonal Antibodies Research
  • Lanthanide and Transition Metal Complexes
  • Viral Infectious Diseases and Gene Expression in Insects
  • Electron Spin Resonance Studies

Novartis (Slovenia)
2024

Administration of monoclonal antibodies (mAbs) is currently focused on subcutaneous injection associated with increased patient adherence and reduced treatment cost, leading to sustainable healthcare. The main bottleneck low volume that can be injected, requiring highly concentrated mAb solutions. latter results in solution viscosity pronounced aggregation propensity because intensive protein-protein interactions. Small molecule excipients have been proposed restrict the interactions,...

10.1016/j.ijpharm.2024.124055 article EN cc-by-nc International Journal of Pharmaceutics 2024-03-28
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