William C. Culp

ORCID: 0009-0006-5153-1639
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About
Contact & Profiles
Research Areas
  • Acute Ischemic Stroke Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Ultrasound and Hyperthermia Applications
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Hemodynamic Monitoring and Therapy
  • Ultrasound in Clinical Applications
  • Intracranial Aneurysms: Treatment and Complications
  • Airway Management and Intubation Techniques
  • Photoacoustic and Ultrasonic Imaging
  • Stroke Rehabilitation and Recovery
  • Anesthesia and Pain Management
  • Vascular Procedures and Complications
  • Central Venous Catheters and Hemodialysis
  • Respiratory Support and Mechanisms
  • Neurological Disorders and Treatments
  • Organ Transplantation Techniques and Outcomes
  • Radiation Dose and Imaging
  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Aortic aneurysm repair treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Ultrasound and Cavitation Phenomena
  • Cardiac Imaging and Diagnostics

University of Arkansas Medical Center
2002-2025

Baylor Medical Center at Garland
2020-2025

Baylor College of Medicine
2023-2025

Baylor Scott & White Health
2013-2025

Baylor Scott & White Medical Center - Temple
2018-2024

Temple College
2016-2023

Texas A&M University
2006-2021

University of Arkansas for Medical Sciences
2011-2020

Texas A&M University System
2005-2020

Mentor
2014-2020

Background and Purpose— Destruction of microbubbles by transcutaneous low-frequency ultrasound (LFUS) has been used to lyse adjacent clot recanalize acutely thrombosed vessels. LFUS with intraarterial shown cerebral rapidly in pigs without thrombolytic drugs. We hypothesized that intravenous platelet-targeted may be a rapid noninvasive technique intracerebral Methods— After angiography, 0.5 cc autogenous thrombus was injected into 1 ascending pharyngeal artery pig, occluding it the rete...

10.1161/01.str.0000140890.86779.79 article EN Stroke 2004-08-20

Background and Purpose— Microbubbles (MB) combined with ultrasound (US) have been shown to lyse clots without tissue-type plasminogen activator (tPA) both in vitro vivo. We evaluated sonothrombolysis 3 types of MB using a rabbit embolic stroke model. Methods— New Zealand White rabbits (n=74) received internal carotid angiographic embolization single 3-day-old cylindrical (0.6×4.0 mm). Groups included: (1) control (n=11) embolized treatment; (2) tPA (n=20); (3) tPA+US (n=10); (4) perflutren...

10.1161/strokeaha.110.607150 article EN Stroke 2011-06-25

Introduction: Tissue plasminogen activator (tPA) is the thrombolytic standard of care for acute ischemic stroke, but intracerebral hemorrhage (ICH) remains a common and devastating complication. We investigated using ultrasound (US) microbubble (MB) techniques to reduce required tPA doses decrease ICH. Materials Methods: Fresh blood clots (3–5 hours) were exposed in vitro (0.02 or 0.1 mg/mL) plus pulsed 1 MHz US (0.1 W/cm2), with without 1.12 × 108/mL MBs (Definity albumin/dextrose [adMB])....

10.1097/rli.0b013e318200757a article EN Investigative Radiology 2010-12-11

To determine initial and long-term results of metal stent placement in biliary strictures that failed to respond balloon dilation.Sixty-one stents were placed 36 liver transplant recipients (age range, 3 months 71 years) with dilation. Patients followed up for 5 years.Initial was successful all patients. Primary patency 44% at years 0% years; secondary maintained 88% those intervals. Patency associated the Gianturco Z superior Palmaz stent. Stents located anastomotic sites had higher rates...

10.1148/radiology.199.2.8668775 article EN Radiology 1996-05-01

Background: A new, miniaturized ultrasound device, the pocket echocardiograph (PE), is highly portable and can be carried inside a lab‐coat pocket. Studies of this device are limited have not examined use by novice echocardiographers. We hypothesize that echocardiographer PE to produce interpretable cardiac images, both expert echocardiographers accurately quantify ejection fraction. Methods: Unselected subjects (n = 40) in an echocardiography laboratory underwent blinded formal...

10.1111/j.1540-8175.2009.01125.x article EN Echocardiography 2010-04-16

Objectives: Increasing evidence confirms that microbubble (MB)-augmented ultrasound (US) thrombolysis enhances clot lysis with or without tissue plasminogen activator (tPA). Intracranial hemorrhage (ICH) is a major complication militating against tPA use in acute ischemic stroke. We quantified the incidence of ICH associated and MB + US therapy compared infarct volumes rabbit model Materials Methods: Rabbits (n = 158) received 1.0-mm clot, angiographically injected into internal carotid...

10.1097/rli.0b013e31820e143a article EN Investigative Radiology 2011-02-23

Over 600 operating room fires occur annually although many cases go unreported. 81% of involve surgical drapes, yet limited data exist on the differing degrees flammability drapes and other fuel sources in varying oxygen concentrations. The purpose this study is to assess characteristics fuels under concentrations.Five were analyzed three levels oxygen: 21%, 50%, 100%. Three test samples each material burned a manner similar that established by Consumer Product Safety Commission. Time sample...

10.1097/aln.0b013e3182a35303 article EN Anesthesiology 2013-07-18

Patient handoffs are high-risk times associated with sentinel events. Effective handoff processes may enhance patient safety and team member communication. This study assesses the impact of a standardized protocol for from cardiac surgery operating room to intensive care unit (ICU).Using prospective pre-post design, formalized process was developed including critical elements procedure, script, checklist. Data were collected 60 observations (30 pre 30 post), evaluating 52 unique parameters,...

10.1097/01.jhq.0000460123.91061.b3 article EN Journal for Healthcare Quality 2015-01-01
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