- Reproductive Biology and Fertility
- Prenatal Screening and Diagnostics
- Ovarian function and disorders
- Gestational Trophoblastic Disease Studies
- Renal and related cancers
- Impact of Technology on Adolescents
- Ultrasound and Hyperthermia Applications
- Immune Cell Function and Interaction
- Multiple Sclerosis Research Studies
- T-cell and B-cell Immunology
- Genetic Syndromes and Imprinting
- Child Development and Digital Technology
- Assisted Reproductive Technology and Twin Pregnancy
- Pluripotent Stem Cells Research
- Social and Educational Sciences
Aarhus University Hospital
2013-2024
Aarhus University
2013-2015
STUDY QUESTIONHow consistent is the time-lapse annotation of dynamic and static morphologic parameters embryo development, within between observers?
STUDY QUESTIONTo what extent do patient- and treatment-related factors explain the variation in morphokinetic parameters proposed as embryo viability markers?
How does tetraploidy develop in hydatidiform moles (HMs), and what is the frequency of different origins?Most molar pregnancies with tetraploid cells appear to be produced by somatic endoreduplications, while a minority originate from zygote. The zygotic was estimated 0.7%.The parental origin genome HMs has only been evaluated few cases, most showing three sets father (PPPM). Estimates proportion that are vary between 2 28%.From 1986 2010, unfixed samples clinically suspected were forwarded...
Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods and non‐diseased symptomatic controls (SC) were activated vitro with or without αCD46 antibody co‐stimulation. Cytokine responses measured assess T‐cell responsiveness. The fold difference between αCD3/CD46 αCD3/isotype was calculated determine enhancement activation compared...
Abstract Conventional MRI is crucial for diagnosing multiple sclerosis (MS) but lacks precision, leading to the clinico-radiological paradox and misdiagnosis risk, especially when confronted with unspecific lesions not related MS. Advancements in perfusion-weighted imaging (PWI) an algorithm designed diseases anticipated contrast agent extravasation offer insight into microvascular impairment flow heterogeneity. Our study aimed assess these factors MS patients their association clinically...