Linlin Zhang

ORCID: 0009-0006-8470-1868
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About
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Research Areas
  • Air Quality and Health Impacts
  • Energy and Environment Impacts
  • Meteorological Phenomena and Simulations
  • Atmospheric chemistry and aerosols
  • Vehicle emissions and performance
  • Metaheuristic Optimization Algorithms Research
  • Advanced Multi-Objective Optimization Algorithms
  • Nutrition and Health in Aging
  • Text and Document Classification Technologies
  • Lung Cancer Diagnosis and Treatment
  • Global Cancer Incidence and Screening
  • Plant Pathogens and Fungal Diseases
  • Evolutionary Algorithms and Applications
  • Process Optimization and Integration
  • Tropical and Extratropical Cyclones Research
  • Orthodontics and Dentofacial Orthopedics
  • Protist diversity and phylogeny
  • Lung Cancer Treatments and Mutations
  • Sentiment Analysis and Opinion Mining
  • Food Industry and Aquatic Biology
  • Enhanced Recovery After Surgery
  • Humor Studies and Applications
  • Lung Cancer Research Studies
  • Clinical Nutrition and Gastroenterology
  • Ocean Waves and Remote Sensing

XinHua Hospital
2025

Shanghai Jiao Tong University
2025

Nantong University
2024

Shandong University
2024

Yancheng First People's Hospital
2024

Beijing University of Technology
2022-2023

China National Environmental Monitoring Center
2011-2020

Shandong University of Science and Technology
2017-2019

Tongji University
2015-2017

131I therapy is clinically unfeasible for anaplastic thyroid carcinoma (ATC), due to lack of active targets and ATC's resistance radiation. Novel radionuclide-labeled targeted nano-drug delivery systems have exhibited the potential prominent tumor imaging remedy. Capitalizing on recent research achievements in nanotechnology nuclear medicine, we sought develop a radiolabeled nano-drug, which could specifically accumulate ATCs via tumor-selective system treat tumors with both radionuclide...

10.1186/s12951-025-03223-2 article EN cc-by-nc-nd Journal of Nanobiotechnology 2025-03-06

PM2.5 and PM10 samples were collected simultaneously in each season Beijing, Tianjin Shijiazhuang to identify the characteristics of water-soluble ion compositions North China Plain. The ions displayed significant seasonal variation. dominant NO3−, SO42−, NH4+ Cl−, accounting for more than 90% 86% mass total PM10, respectively. anion/cation ratio indicated that acidity city varied both between sites seasonally. Over 50% species enriched small particles ≤1 µm diameter. [NO3−]/[SO42−] vehicles...

10.1371/journal.pone.0113831 article EN cc-by PLoS ONE 2014-12-01

Abstract Outdoor air pollution is a growing public health concern, particularly in urban settings. However, there are limited epidemiological data on outdoor rural areas with substantial levels of attributed to solid fuel burning for household cooking and heating. Xuanwei Fuyuan counties China where the domestic combustion locally sourced bituminous (“smoky”) coal has been associated highest lung cancer rates China. We previously assessed indoor personal exposures this area; however,...

10.1038/s41598-020-68229-2 article EN cc-by Scientific Reports 2020-07-09

Conditional nonlinear optimal perturbation (CNOP) is an extension of linear singular vector(LSV) to optimization. Generally, CNOP solved with such adjoint based algorithms as SPG2, SQP. Unfortunately, it often difficult obtain the corresponding models for some models. In addition, containing discontinuous "on-off" switches, methods can hardly find correct gradient direction solving CNOP. These two factors restrict application Intelligence are utilized handle these problems and has made...

10.1109/ijcnn.2015.7280522 article EN 2022 International Joint Conference on Neural Networks (IJCNN) 2015-07-01

10.1007/s11390-017-1753-8 article EN Journal of Computer Science and Technology 2017-07-01

Anlotinib and apatinib, both vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR-TKIs), are clinically established in the treatment of advanced non-small cell lung cancer (NSCLC) China, with anlotinib emerging as a standard strategy. This study was conducted to evaluate efficacy safety apatinib anlotinib, compare their differences treating patients NSCLC.

10.2147/ott.s468932 article EN OncoTargets and Therapy 2024-08-01

<title>Abstract</title> Background: Many rural areas lack screening for breast cancer. This study employs the RE-AIM framework to assess implementation, effectiveness, and sustainability of a cancer program in China provide insights into developing an effective implementation strategy suitable with limited health resources. Methods: mixed-methods evaluated Ordos, Inner Mongolia, using quantitative qualitative approaches. Quantitative data from 2016 2020 were gathered through surveys results...

10.21203/rs.3.rs-5284188/v1 preprint EN cc-by Research Square (Research Square) 2024-10-29

The index of dominance (S), average crowding (X*), niche breadth (Bi), and overlap (Qik ) dominant zooplankton species were calculated using data collected from four surveys May 2016 to February 2017 in Yueqing Bay, Zhejiang Province. results showed that there 17 (with S>0.02). values those differed greatly positively correlated with S. overlaps zooplanktons extremely low. total amount pairs higher than 0.6 (Qik>0.6) 25 which represented 18.4% the pairs. Results redundancy analysis...

10.13287/j.1001-9332.202101.039 article EN Journal of Applied Ecology 2021-01-01

Abstract Residents in Xuanwei, China have the highest lung cancer incidence rates for both men and women, despite fact that almost all women are non-smokers. Several lines of research provided strong support excess rate this region is caused primarily by emissions from smoky coal exposure. We carried out a hospital-based case-control study non-smoking female Xuanwei its neighboring county, Fuyuan, to identify which constituents combustion other indoor environmental exposures causing high...

10.1158/1538-7445.am2011-1876 article EN Cancer Research 2011-04-01

Backgrounds and aims: Residents in Xuanwei, China have the highest lung cancer incidence rates for both men women. Several lines of research provided strong support that excess rate this region is caused primarily by emissions from smoky coal exposure. In order to develop individual estimates exposure known or suspected carcinogens an ongoing case-control study, we designed a comprehensive assessment study 163 households evaluate PAHs, PM2.5, silica, other exposures wood burning. Methods:...

10.1289/isee.2011.00524 article EN ISEE Conference Abstracts 2011-09-13
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