Objective To compare patient characteristics and disease burden between men women with axial spondyloarthritis (axSpA) in the US-based Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry. Methods Patients aged ≥ 18 years axSpA enrolled PsA/SpA Registry March 2013 November 2018 who were not concurrently diagnosed PsA included. Patient demographics, clinical characteristics, activity, patient-reported symptoms, work productivity, treatment history at enrollment compared women,...

Rheumatoid arthritis (RA), psoriatic (PsA), and axial spondyloarthritis (axSpA) are three common inflammatory rheumatic diseases that can lead to deformities joint destruction. Few studies have compared disease burden across patients with these diseases. The objective of this study was compare in RA, PsA, or axSpA routine US clinical practice. This included adults enrolled the Corrona RA PsA/SpA registries between March 2013 2018. Patient characteristics at enrollment were vs. PsA using t...

Objective To compare the characteristics of patients with axial spondyloarthritis (axSpA) who had enthesitis versus those without enthesitis. Methods This study included adult axSpA enrolled in Corrona Psoriatic Arthritis/Spondyloarthritis Registry (March 2013 to August 2018). Enthesitis was assessed at enrollment via Spondyloarthritis Research Consortium Canada Index. Characteristics were compared between and using t tests or Wilcoxon rank‐sum for continuous variables χ 2 Fisher exact...

The average delay in diagnosis for patients with axial spondyloarthritis (axSpA) is 7 to 10 years. Factors that contribute this are multifactorial and include the lack of diagnostic criteria (although classification exist) axSpA difficulty distinguishing inflammatory back pain, a key symptom axSpA, from other highly prevalent forms low pain. We sought describe reasons provided by primary care physicians.We conducted qualitative research study which included 18 US physicians, balanced gender....

First-generation Latine college students (FGLCS) can experience a cultural mismatch between their collectivistic norms and the individualistic culture of American universities. Our study ( N = 145), conducted at an R1 west coast Hispanic-Serving Institution, examined how social support influences FGLCS’ experiences. Results showed family friend are important for university fit, that friends, family, use campus services contribute to belonging. who held more interdependent motives reported...

Introduction: Human Immunodeficiency Virus (HIV) and Acquired Syndrome (AIDS) continue to be significant global public health issues, affecting millions of people worldwide. Despite ongoing efforts in education awareness, misconceptions stigmatising attitudes toward individuals living with HIV/AIDS persist many communities, including among future healthcare professionals. This study was designed evaluate both the level HIV/AIDS-related knowledge extent clinical medical students enrolled at...

BACKGROUND: The Health Assessment Questionnaire Disability Index (HAQ-DI) has been validated and widely used in psoriatic arthritis (PsA) clinical trials for the assessment of patient functional status. Significant improvements HAQ-DI have reported response to therapeutic interventions; however, few US studies evaluated economic impact disability patients with PsA. OBJECTIVE: To evaluate association status health care resource utilization (HCRU) total costs diagnosed METHODS: This...

Early diagnosis of ankylosing spondylitis (AS) remains challenging because the high prevalence chronic back pain in patients initially treated by nonrheumatology health care providers (HCPs). We assessed patient pathway to rheumatology referral, including HCP recognition inflammatory (IBP) and other features suggestive AS, diagnostic workup, treatment, referral a specialist with goal identifying barriers rheumatologist.US HCPs from 10 specialties were invited participate cross-sectional...

On average, patients with axial spondyloarthritis (axSpA) suffer from symptoms up to 13 or more years before diagnosis, contributing psychological distress and healthcare burden METHODS: We conducted six semi-structured focus groups 26 axSpA (from 3 rheumatology practices located in the states of Massachusetts, Colorado, Pensylvania, USA) exploring early disease diagnostic experiences. Verbatim transcripts were coded using a start list emerging thematic codes added. A qualitative analysis...

BACKGROUND: Interventions for ankylosing spondylitis (AS) have improved patient-reported outcomes (PROs) in clinical studies. However, limited data exist associating these improvements with health care resource utilization (HCRU) or cost savings. Few studies evaluated the economic impact of physical status and related disease burden patients AS United States. OBJECTIVE: To assess association PRO measures HCRU costs from a national US registry. METHODS: This cohort study included adults...

The study objective was to explore differences in ankylosing spondylitis (AS) diagnosis experiences between men and women by examining the coding of health events over 2 years preceding AS diagnosis.Claims data (January 2006-April 2019) from MarketScan databases were examined. Patients who had received two or more diagnoses at least 30 days apart insurance enrollment before their first analyzed. Men matched 1:1 age, date, type, duration. Health (diagnosis provider codes) examined stratified...

Background Many patients with axial spondylarthritis (axSpA) experience lengthy diagnostic delays upwards of 14 years. (5–14 years). Screening tools for axSpA have been proposed use in primary care settings, but whether this approach could be implemented into busy settings remains unknown. Objective To solicit feedback from physicians regarding questions the Inflammatory Back Pain Assessment: Assessment Spondyloarthritis International Society (ASAS) Expert Criteria and gain insight about...

Costs associated with biologic switching and discontinuation can be high in psoriatic arthritis (PsA), their inappropriate use may have cost implications for patients, healthcare professionals, payers. To compare direct costs of treatment switchers, non-switchers, discontinuers among patients PsA who newly initiated a biologic. Patients aged ≥ 18 years 1 pharmacy claim an FDA-approved subcutaneous from January 2016 to 31 December were identified the Truven Health MarketScan Databases....

The average time to a diagnosis for people with axial spondyloarthritis (axSpA) is 7-10 years. Delayed may result in increased structural damage, worse physical function, and quality of life relative patients timely axSpA diagnosis. Understanding patient experiences provide insights how reduce diagnostic delays.To foundational knowledge about healthcare providers leading an diagnosis.We conducted exploratory qualitative research study six focus groups interviews participants recruited from...

<h3>Background:</h3> There is a significant delay in the diagnosis of ankylosing spondylitis (AS) United States. Several studies have estimated that time between symptom onset and physician 5-7 years. Diagnosis attributed to nonspecific presentation chronic back pain, requiring clinical experience recognize early AS. <h3>Objectives:</h3> To identify obstacles AS by assessing knowledge nonrheumatology health care providers (HCPs) on inflammatory pain (IBP) possible barriers referral...

Costs associated with biologic switching and discontinuation can be high in chronic inflammatory diseases. Inappropriate use of medications may have cost implications for both payers patients. Understanding utilization rates is lacking among patients ankylosing spondylitis (AS).To compare direct costs treatment switchers, nonswitchers, discontinuers AS who newly initiated a biologic.Patients aged ≥ 18 years an diagnosis 1 pharmacy claim FDA-approved subcutaneous between January 1, 2016,...

<h3>Background</h3> Axial spondyloarthritis (AxSpA) is a chronic inflammatory rheumatic disease that primarily affects the axial skeleton and frequently peripheral joints entheses. AxSpA encompasses ankylosing spondylitis nonradiographic AxSpA. Sex differences have been described for patient reported outcomes (PROs) in SpA; however, more research needed to better understand overall clinical burden of women, particularly United States. <h3>Objectives</h3> To compare demographics,...

<h3>Background</h3> Enthesitis is a common extra-axial manifestation in patients with axial spondyloarthritis (AxSpA)^1,2; however, not much known about the prevalence of enthesitis AxSpA and its impact on disease burden US real-world settings. <h3>Objectives</h3> This study describes characteristics who had vs without enthesitis. <h3>Methods</h3> included aged ≥ 18 years enrolled Corrona PsA/SpA Registry between March 2013 August 2018. at enrollment was assessed via...

The aim of this study was to understand the reasons for canakinumab initiation among patients with Still's disease, including systemic juvenile idiopathic arthritis (SJIA) and adult-onset disease (AOSD), in US clinical practice.Physicians retrospectively reviewed medical charts (regardless age at symptom onset) who were prescribed from 2016 2018. Patients aged < 16 years onset classified as having SJIA those ≥ (calculated case-record forms) AOSD. Patient treatment history physician analyzed....

Background People with axial Spondyloarthritis (axSpA) suffer from lengthy diagnostic delays of ~7 years. The usage screening tools to identify axSpA patients in primary care can reduce by facilitating early referral rheumatologic care. purpose this study was examine the psychometric properties a potential tool for axSpA. Method Content validity evaluated soliciting feedback 7 rheumatologists regarding relevance and content representativeness proposed questions. For test-retest study,...

<h3>Background</h3> Secukinumab is the first non–tumor necrosis factor inhibitor biologic therapy approved for treatment of ankylosing spondylitis (AS) in United States. Patients with AS clinical trials who receive biologics, including secukinumab, may not be representative those treated real-world practice due to differences patient characteristics, patterns, physician experience, and insurance coverage (ie, access). Few studies have characterized patients initiate secukinumab. The Corrona...