A5111847036- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Chromosomal and Genetic Variations
- Acute Lymphoblastic Leukemia research
- Genomic variations and chromosomal abnormalities
- Prenatal Screening and Diagnostics
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Chronic Lymphocytic Leukemia Research
- Maternal and Neonatal Healthcare
- Vector-borne infectious diseases
- Virology and Viral Diseases
- Mosquito-borne diseases and control
- DNA Repair Mechanisms
- Sexual Differentiation and Disorders
- Genomics and Chromatin Dynamics
- Retinoids in leukemia and cellular processes
- Hepatitis B Virus Studies
- Helminth infection and control
- Genomics and Rare Diseases
- Cystic Fibrosis Research Advances
- Animal Genetics and Reproduction
- Carcinogens and Genotoxicity Assessment
- Infectious Diseases and Tuberculosis
- Neurobiology and Insect Physiology Research
- Dermatological and COVID-19 studies
Instituto Gulbenkian de Ciência
2025
Instituto Nacional de Pediatria
2007
Johns Hopkins University
2007
Centro de Genética Clínica
1990-2005
University of San Carlos of Guatemala
2003
Hospital de Magalhães Lemos
1989
University of the Witwatersrand
1980-1988
South African Institute for Medical Research
1980-1987
Instituto Português de Malacologia
1946
Guillain-Barré syndrome (GBS) is an acute, immune-mediated flaccid paralysis frequently associated with Campylobacter infection. Of two predominant GBS subtypes, a demyelinating subtype (acute inflammatory demyelinative polyneuropathy [AIDP]) predominates in the United States and Europe, axonal motor neuropathy [AMAN]) form China. Previous clinical studies suggested that AMAN also occurs Mexican children. The purpose of this study was to describe subtypes children from Mexico City.We...
S ummary . Four patients representing a spectrum of haematological malignancies are reported. Two had Philadelphia chromosome negative myeloproliferative disorders, one acute lymphoblastic leukaemia and eosinophilic leukaemia. In each case eosinophilia was present demonstrated to be part the malignancy by association clonally abnormal metaphases with eosinophil granules. Abnormalities involving short arm 12 (12p 13) were constant feature in all four cases therefore nonrandom between this...
Three hundred and forty seven rats belonging to the Mastomys natalensis complex (Smith, 1834) were live trapped from 60 localities in southern Africa. They identified as species A, or B using either both diploid chromosome number haemoglobin electromorphs. These, previously published data are presented give a distribution of It is suggested that workers may safely use marker for identification purposes this region opposed more difficult marker. We suggest A can be referred M. 1834), coucha...
The dissemination of malignant cells to the brain is a late-stage complication cancer, leading significant morbidity and mortality. Brain metastases (BM) affect 20–30% cancer patients, primarily originating from lung breast melanoma. Despite advances in molecular-targeted therapies, metastatic disease remains incurable, with poor median survival ≤12 months if left untreated. lack therapeutic efficacy mainly attributed presence blood–brain barrier (BBB) genetic differences between BM their...
S ummary . A patient with acute megakaryoblastic leukaemia is described in whom exactly the same paracentric inversion of 3q was detected as three previously documented cases. The patient's serum thrombopoietin (TSF) significantly raised. Based on these findings we postulate a role for gene (? oncogene) chromosome production. Abnormalities may assist delineating subgroup nonlymphocytic leukaemia, namely leukaemia.
Cytogenetic studies on a 17-year-old phenotypic male, with short stature and clinical hormonal features of hypogonadism similar to those an XX revealed X;Y translocation, karyotype, 46,Xt(X;Y)(p22;?p11?q11). He was H-Y antigen positive. X inactivation showed the abnormal in majority cells (60 70%) normal remaining cells. Gene marker studies, including Xg blood grouping, no anomalous segregation. This patient is second reported male showing positively identified tanslocation detectable free Y...
The attempts of Chorine (1938), Gavrilov Gavrilov, Bobkoff & Laurencin (1938) and Rita (1940) to infect chick embryos with Plasmodium gallinaceum, using either a suspension sporozoites or infected blood, yielded negative results. They tried inoculation by deposition the infecting material on chorion-allantois injection into blood vessel this membrane, results observed led make various deductions comparing them other infections which appear in embryo not adult animal.
A molecular phylogeographic study of Paragonimus mexicanus collected from Guatemala and Ecuador was performed. Genomic DNA extracted individual metacercariae, two gene regions (partial mitochondrial cytochrome c oxidase subunit 1 (CO1) the second internal transcribed spacer nuclear ribosomal repeat (ITS2)) were amplified by polymerase chain reaction (PCR). Sequences segregated in a phylogenetic tree according to their geographic origins. ITS2 sequences differed at only one site. Pairwise...
The Giemsa-banded karyotype of the chacma baboon, <i>Papio ursinus, </i>was shown to be identical that hamadryas</i>. Comparison G-banded <i>P</i>. <i>ursinus </i>(PUR) chromosomes with those man (HSA) showed close morphological homoeology between PUR and HSA 5, 8, 12, 19, X, partial homology for seven other chromosomes. 10 a striking resemblance 15 22 was only </i>chromosome containing nucleolar organizer region (NOR). This baboon chromosome,...
A case of mosaicism for tetrasomy 18p detected prenatally is reported. We believe this the second where fetal anomalies were found at autopsy. Copyright © 1998 John Wiley & Sons, Ltd.