A5083031430- Natural product bioactivities and synthesis
- Computational Drug Discovery Methods
- Ethnobotanical and Medicinal Plants Studies
- Microbial Natural Products and Biosynthesis
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- thermodynamics and calorimetric analyses
- Pharmacological Effects of Natural Compounds
- Synthesis and biological activity
- Chromatography in Natural Products
- Plant and fungal interactions
- Natural Antidiabetic Agents Studies
- Bioactive Compounds and Antitumor Agents
- Lichen and fungal ecology
- Biological Stains and Phytochemicals
Universiti Malaysia Pahang Al-Sultan Abdullah
2021-2024
Southeast University
2020-2021
Due to the rising increase in infectious diseases brought on by bacteria and anti-bacterial drug resistance, antibacterial therapy has become difficult. The majority of first-line antibiotics are no longer effective against numerous germs, posing a new hazard global human health 21st century. Through drug-likeness screening, 184 usnic acid derivatives were selected from an in-house database 340 compounds. pharmacokinetics (ADMET) prediction produced fifteen hit compounds, which lead molecule...
Interleukin-6 (IL-6) is a cytokine that involved in the different phases of wound healing. It responsible for promoting inflammation, regulating tissue repair scar formation, stimulating production extracellular matrix components and recruiting immune cells to site. Therefore, suppressing IL-6 beneficial However, no small molecules are currently available market against IL-6. As result, this research gap motivates us find potential inhibitor. This study aimed investigate healing novel...
This research investigated a UPLC-QTOF/ESI-MS-based phytochemical profiling of Combretum indicum leaf extract (CILEx), and explored its in vitro antioxidant vivo antidiabetic effects Long–Evans rat model. After one-week intervention, the animals’ blood glucose, lipid profile, pancreatic architectures were evaluated. UPLC-QTOF/ESI-MS fragmentation CILEx eight docking-guided compounds further dissected to evaluate their roles using bioinformatics-based network pharmacological tools. Results...
Abstract Background In an attempt to explore the scientific basis for pharmacological benefits antioxidant and antimicrobial activities of Ipomoea mauritiana whole plant methanol extract were assessed. Methods The total phenolic flavonoid content determined using standard method while activity was by DPPH free radical scavenging method. evaluated disk diffusion compared with kanamycin (30 μg/disc). Results results revealed that I. contains tannin, saponin, terpenoids, alkaloid flavonoids....
The current data report describes the predictive identification of phytochemical constituents in bioactive extract Ipomoea mauritiana (IM) whole plant. For several formulations this plant was commonly used as 'Vidari' for Ayurvedic medicine. Traditionally, IM tubers are to alleviate spinal cord pain, improve breast milk, a tonic, increase sperm count and treating jaundice. methanol can potentially scavenge free radicals possess antibacterial activity that could be correlated with its...