A5108952967- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Mechanical Circulatory Support Devices
Southern Medical University
2024-2025
Guangdong Provincial People's Hospital
2024-2025
South China Sea Institute Of Oceanology
2025
Guangdong Academy of Medical Sciences
2024-2025
This study investigates the molecular mechanisms and hub genes in idiopathic rupture of mitral valve chordae tendineae (iRCT). Histological changes were assessed via pathological staining, transcriptome sequencing was performed on samples from 8 iRCT patients 6 controls. Differentially expressed (DEGs), functional enrichment, PPI networks, immune cell infiltration analyzed. Hub gene expression validated using RT-qPCR. exhibited proliferation, disorganized collagen fibers, elastin fiber...
Tricuspid valve replacement (TVR), although accounting for a minority of heart surgeries, poses significant challenges, including poor patients' condition, prosthetic complications, and increased perioperative mortality rates. Despite preferences valvuloplasty, some cases necessitate replacement. The choice tricuspid type remains controversial, there is no consensus on surgical risk factors. Additionally, long-term follow-up reports large number are lacking. In this study, we aimed to...
Acute type A aortic dissection (ATAAD) poses significant challenges in cardiovascular management due to its high morbidity and mortality rates. Postcardiotomy cardiogenic shock (PCS) is a severe complication following ATAAD repair that complicates postoperative recovery. Extracorporeal membrane oxygenation (ECMO) has emerged as potential life-saving intervention this context, yet the specific outcomes related ECMO patients remain insufficiently studied.