A5036116828- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- DNA and Nucleic Acid Chemistry
- Crystallography and molecular interactions
- RNA and protein synthesis mechanisms
- Synthesis and Characterization of Heterocyclic Compounds
- Advanced biosensing and bioanalysis techniques
- Geological formations and processes
- Coastal and Marine Dynamics
- Molecular Sensors and Ion Detection
- Supramolecular Self-Assembly in Materials
- Supramolecular Chemistry and Complexes
- Synthesis and Reactivity of Heterocycles
- Coastal wetland ecosystem dynamics
- Hydrology and Sediment Transport Processes
- Enzyme Structure and Function
- Lung Cancer Treatments and Mutations
- Medical Research and Treatments
- Porphyrin and Phthalocyanine Chemistry
- Chemical Synthesis and Analysis
- Soil erosion and sediment transport
- HIV/AIDS drug development and treatment
- Cancer therapeutics and mechanisms
- Click Chemistry and Applications
- Quinazolinone synthesis and applications
Shandong Normal University
2022-2025
Sichuan University
2017-2023
West China Hospital of Sichuan University
2018-2023
Louisiana State University
2023
CeNTech
2019-2021
Chengdu University
2018
Institute of Medicinal Plant Development
2018
Anthropogenic activities and climate change have increased the stress on world’s estuaries over past decades. Limited knowledge exists about how estuarine receding responds to human interference, particularly geomorphic dynamics of channels sandbars. Here, we evaluate topographic evolution upper Yangtze River Estuary (YRE), largest branch reach with frequently shifting sandbars, from 1994 2019. Our results show that a net channel erosion 9.59 × 108 m3 occurred in YRE, equivalent an annual...
Abstract Stabilization of DNA is beneficial for many applications in the fields therapeutics, diagnostics, and materials science. Now, this phenomenon studied on heterochiral DNA, an autonomous recognition system with complementary strands α‐D β‐D configuration showing parallel strand orientation. The 12‐mer duplexes were constructed from anomeric (α/β‐D) oligonucleotide single‐strands. Purine‐2,6‐diamine 8‐aza‐7‐deaza‐7‐bromopurine‐2,6‐diamine 2′‐deoxyribonucleosides having capability to...
Abstract Heterochiral DNA with hydrogen‐bonded and silver‐mediated base pairs have been constructed using complementary strands nucleosides α‐ d or β‐ configuration. Anomeric phosphoramidites were employed to assemble the oligonucleotides. According T m values thermodynamic data, duplex stability of heterochiral duplexes was similar that homochiral DNA, but mismatch discrimination better in DNA. Replacement purines by 7‐deazapurines resulted stable parallel duplexes, thereby confirming...
The global demand for sand and gravel is at 50 billion tons per year, far exceeding resource capacities. It reached 7.6 in 2021 the Yangtze River Basin (YRB), China. However, production severely limited YRB. Therefore, incongruity between supply of river prominent. Wise management decreasing resources YRB has become critical since Three Gorges Dam became operational 2003. This study synthesized spatial temporal changes mining activities quantities along its major tributaries from 2004 to...
Isolated and consecutive heterochiral α-dC- base pairs have been incorporated into 12-mer oligonucleotide duplexes at various positions, thereby replacing Watson-Crick pairs. To this end, a new synthesis of the α-d anomer dC has developed, oligonucleotides containing α-dC residues synthesized. Silver-mediated were formed upon addition silver ions. Furthermore, we established that α-dC-dC can approach stability pair, whereas homochiral dC-dC are significantly less stable. A positional change...
The crystal structures of halogenated 1,2,4-triazolo[1,5-<italic>a</italic>]pyridine derivatives disclose intriguing structural chemistry features dictated by the formation either hydrogen bonds (HBs) or halogen (XBs).
β-2'-Deoxyribonucleosides are the constituents of nucleic acids, whereas their anomeric α-analogues rarely found in nature. Moreover, not much information is available on structural and conformational parameters α-2'-deoxyribonucleosides. This study reports single-crystal X-ray structure α-2'-deoxycytidine, C
Hydrogen bond (HB) mediated base pair motifs are versatile scaffolds of diverse supramolecular constructs. Here, we report that two new four- and six-membered supermacrocyclic assemblies with intriguing geometries could self-assemble from adenine derivatives, APN (1) APC (2). The conversion a conventional HB acceptor, N8 1, to non-conventional donor, C8-H 2, had pronounced impact on the overall intricate network self-assembly patterns, epitomizing subtleties in design exploitation such...
Reduction in river discharge and sediment load has left deltaic lobes the world’s many deltas starving, but knowledge of how subaqueous topography these abandoned subdeltas responds to environmental changes is limited. In this study, we aimed determine long-term dynamics seabed delta advance current knowledge. As a case selected an subdelta on Yellow River Delta Bohai Sea, China, for which three-decade long (1984–2017) bathymetric data records are available. We analyzed seafloor surface...
Harmonious quaternary interactions consisting of G*–Ag and CH + –NO 3 − base pairs are disclosed in a mixed hydrogel system.