A5060213438- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Pressure Ulcer Prevention and Management
- Surgical Sutures and Adhesives
- Periodontal Regeneration and Treatments
- Tendon Structure and Treatment
- Mesenchymal stem cell research
- Shoulder Injury and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Tissue Engineering and Regenerative Medicine
- Myofascial pain diagnosis and treatment
Christie's
2013
Reynolds American (United States)
2009
American Health Network
2008
Introduction. Omega-3–rich fish skin grafts have been shown to accelerate wound healing in full-thickness wounds. Objective. The goal of this study was compare the graft with standard care (SOC) using collagen alginate dressing management treatment-resistant diabetic foot ulcers (DFUs), defined as superficial not involving tendon capsule or bone. Materials and Methods. Patients DFUs who were first treated SOC (offloading, appropriate debridement, moist care) for a 2-week screening period...
DFUs remain a cause of significant morbidity.This is the third 3 planned articles reporting on prospective, multicenter, randomized controlled trial evaluating use omega-3-rich acellular FSG compared with CAT in management DFUs.A total 102 patients DFU (n = 51 FSG, n CAT) participated as ITT candidates, 77 those included PP analysis 43 34 CAT). Six months after treatment, healed ulcers were followed up for ulcer recurrence. A cost model was applied both treatment groups.The proportion closed...
This multicenter, retrospective study presents the use of a human acellular dermal regenerative tissue matrix as an alternative treatment for 100 chronic, full-thickness wounds lower extremity in 75 diabetic patients. Comorbidities included cardiac disease (86.0%), neuropathy peripheral vascular (82.0%), infection (54.0%), obesity (51.0%), and osteomyelitis (37.0%). Wound locations foot ankle (8.0%), (6.0%). Mean wound age was 20.4 weeks (1.3-191.4 weeks). University Texas (UT)...
The objective of this multicenter study was to prospectively evaluate the healing outcomes chronic diabetic foot ulcers (DFUs) treated with PriMatrix (TEI Biosciences, Boston, Massachusetts), a fetal bovine acellular dermal matrix.Inclusion criteria required subjects have DFU that ranged in area from 1 20 cm² and failed heal more than 30% during 2-week screening period when moist wound therapy. For qualifying subjects, secured into clean, sharply debrided wound; dressings were applied...
The suitability of the ovine forestomach matrix (OFM) for treatment recalcitrant wounds was evaluated in 19 patients. At 12 weeks, 50% had closed, and average reduction surface area 73.4%. Promising outcomes this initial series support clinical consideration OFM.
Diabetes and its complications, particularly diabetic foot ulcers (DFUs), pose significant challenges to healthcare systems worldwide. DFUs result in severe consequences such as amputation, increased mortality rates, reduced mobility, substantial costs. The majority of are preventable treatable through early detection. Sensor-based remote patient monitoring (RPM) has been proposed a possible solution overcome limitations, enhance the effectiveness, existing care best practices. However,...
Assessing implanted biological reinforcement graft success in soft-tissue repairs is typically limited to noninvasive measurements and functional outcome measures. However, there are times when a histologic snapshot of the incorporation may be possible owing nongraft-related postoperative complication, such as hardware failure.We histologically evaluated 6-month biopsy sample from an Achilles tendon repair augmented with acellular human dermal matrix (AHDM). A 57-year-old woman was treated...
This is the second of 3 planned articles reporting on a prospective, multicenter, randomized controlled trial assessing efficacy fish skin graft in management diabetic foot ulcers comparison with standard care (collagen alginate dressing).The primary end point this prospective number closed wounds at 12 weeks.As time writing, 94 patients had completed protocol. At 12-week follow-up, healing was achieved 63.0% index (29 46 patients) acellular group compared 31.3% control (15 48 (P =.0036). In...
Diabetic foot ulcers (DFU) are a devastating complication of diabetes. There numerous challenges with preventing diabetic complications and barriers to achieving the care processes suggested in established guidelines. Multi-faceted digital health solutions, which combine multimodal sensing, patient-facing biofeedback, remote patient monitoring (RPM), show promise improving our ability understand, prevent, manage DFUs.
Introduction. CAMPs are used for treating refractory DFUs where other treatments have failed. PLA is a CAMP that has demonstrated effectiveness in promoting healing burns and acute wounds. Objective. A single-center, prospective, randomized controlled trial comparing PLA-guided closure matrices versus collagen dressings was conducted to assess of Wagner grades 1 2 DFUs. Materials Methods. total 30 participants were receive weekly debridement, wound care, DFU offloading plus either or CAMPs....
Diabetes mellitus affects hundreds of millions people worldwide, each which have up to a 25% risk developing diabetic foot ulcer (DFU) during their lifetime. With poor DFU healing rates using standard care, advanced treatments are introduced attempt close the wound. The objective this preliminary clinical evaluation was evaluate lower extremity ulcers treated with novel bioengineered wound product (BWP). BWP, solid absorbable and conformable sheet composed gelatin, Manuka honey,...
Venous leg ulcers (VLUs) and diabetic foot (DFUs) are examples of chronic wounds that pose an ongoing health care challenge. Despite significant progress in managing such wounds, challenges persist require innovative solutions. Cellular, acellular, matrix-like products (CAMPs) advanced therapies designed to facilitate wound healing. Polylactic acid (PLA) is a synthetic material used alloplastic CAMPs has shown promise the management burns traumatic injuries.