- Erythropoietin and Anemia Treatment
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Cardiomyopathy and Myosin Studies
- RNA regulation and disease
- Bipolar Disorder and Treatment
- Ion channel regulation and function
- Liver Disease Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Animal Virus Infections Studies
- Mental Health Research Topics
- Viral Infections and Immunology Research
- Electroconvulsive Therapy Studies
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
Medical University of Lodz
2023-2025
Anemia is one of the most common chronic kidney disease (CKD) complications. It negatively affects patients’ quality life and clinical outcomes. The pathophysiology anemia in CKD involves interplay various factors such as erythropoietin (EPO) deficiency, iron dysregulation, inflammation, bone marrow dysfunction, nutritional deficiencies. Despite recent advances understanding this condition, still remains a serious challenge population patients with CKD. Several guidelines have been published...
Primary electrical heart diseases, often considered channelopathies, are inherited genetic abnormalities of cardiomyocyte behavior carrying the risk malignant arrhythmias leading to sudden cardiac death (SCD). Approximately 54% sudden, unexpected deaths in individuals under age 35 do not exhibit signs structural disease during autopsy, suggesting potential significance channelopathies this group age. Channelopathies constitute a highly heterogenous comprising various diseases such as long QT...
Hepatorenal syndrome (HRS) is a disorder associated with cirrhosis and renal impairment, portal hypertension as its major underlying cause. Moreover, HRS the third most common cause of acute kidney injury, thus creating public health concern. This review summarizes available information on pathophysiological implications HRS. We discuss pathogenesis Mechanisms such dysfunction circulatory system, bacterial infection, inflammation, impaired autoregulation, circulatory, others, which have been...
Reakcja disulfiramowa (ang. disulfiram-ethanol reaction, DER) i reakcja disulfiramopodobna disulfiram-like DLR) definiowane jako ostre zatrucie aldehydem octowym po ekspozycji na etanol wciąż pozostają problemem współczesnej farmakoterapii. Nazwy reakcji pochodzą od leku o nazwie disulfiram, raz pierwszy zarejestrowanego w Stanach Zjednoczonych do leczenia alkoholizmu latach 40. ubiegłego wieku. DER będąca efektem działania disulfiramu polega blokowaniu dehydrogenazy aldehydu octowego (ALDH)...