A5102009661- Peptidase Inhibition and Analysis
- Nanoplatforms for cancer theranostics
- Axon Guidance and Neuronal Signaling
- Gestational Diabetes Research and Management
- Ferroptosis and cancer prognosis
- Extracellular vesicles in disease
- Immune Cell Function and Interaction
- Mathematical and Theoretical Epidemiology and Ecology Models
- Cancer Immunotherapy and Biomarkers
- Pregnancy and preeclampsia studies
- Cardiovascular Disease and Adiposity
- Complex Systems and Time Series Analysis
- Monoclonal and Polyclonal Antibodies Research
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Immune cells in cancer
- Economic theories and models
Dalian Medical University
2023-2025
Second Affiliated Hospital of Dalian Medical University
2023-2025
Lanzhou Jiaotong University
2024
Xuzhou Medical College
2023
Second People’s Hospital of Huai’an
2023
Soochow University
2011
Inhibitory costimulatory molecule CD274 expresses in various cancers and contributes to cancer immune evasion by inhibiting T cell activation proliferation, yet the regulatory mechanisms for overexpression are poorly understood. In this study, we discovered a novel mechanism of expression regulated miR-570. A guanine-to-cytosine mutation at 3'-UTR mRNA led disrupting miR-570 binding. The mutations were widely observed sequencing 276 gastrointestinal (esophageal, gastric, colorectal,...
The intricate interactions between immune cells and tumors exert a profound influence on cancer progression therapeutic efficacy. Within the tumor microenvironment, exosomes have emerged as pivotal mediators of intercellular communication, with their cargo non-coding RNAs (ncRNAs) serving key regulatory elements. This review examines multifaceted roles cell-derived exosomal ncRNAs in biology. involvement various cells, including T B natural killer macrophages, neutrophils, myeloid-derived...
Taking into account the nonlinear demand function, we have developed a multi-agent fishery economic model, where multitude of agents are bounded by rationality. The fishing decisions these driven profit gradient mechanism. To assess local stability system, analysis is performed with Jury criterion. investigation has revealed presence two conventional paths to chaos, namely, flip bifurcation and Neimark–Sacker bifurcation. This was achieved mapping regions curves Nash equilibrium....
Background: To analyse how Semaphorin 6D (SEMA6D) expression and extracellular signal-regulated kinase (ERK), phosphatidylinositol 3-kinase/protein B/mammalian target of rapamycin (PI3K/AKT/mTOR) signal pathways are activated they influence gastric cancer proliferation, migration, invasion. Methodology: SEMA6D was knocked down in human cells using RNA interference technology. In vitro assays were used to knockdown affects clone formation, ERK PI3K/ AKT/mTOR signaling pathway related proteins...