Edward Mignone

ORCID: 0009-0007-8605-0525
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About
Contact & Profiles
Research Areas
  • Neuroendocrine Tumor Research Advances
  • Pituitary Gland Disorders and Treatments
  • Adrenal and Paraganglionic Tumors
  • Head and Neck Surgical Oncology
  • Glioma Diagnosis and Treatment
  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Diet and metabolism studies

Royal Adelaide Hospital
2023-2025

The University of Adelaide
2024

Queen Elizabeth Hospital
2020

More than 10% of adults undergoing colonoscopy have type 2 diabetes (T2D) (1). The use sodium–glucose cotransporter inhibitors (SGLT2i) has increased due to their glycemic control and benefits lowering cardiovascular morbidity mortality as well reducing diabetic nephropathy (2,3). Diabetic ketoacidosis (DKA) is a rare complication associated with SGLT2i. Precipitating factors include fasting, dietary modifications, intercurrent illnesses, surgical stress, insulin insufficiency,...

10.2337/dc20-1244 article EN Diabetes Care 2020-08-17

Summary Multiple endocrine neoplasia type 1 ( MEN1 ) requires a high level of suspicion, and late diagnosis can lead to dire outcomes. Genetic counselling is an important part management, with lack evidence surrounding optimal approach in Aboriginal Australian populations. Our case surrounds remote-dwelling 48-year-old female who was reviewed by inpatient team 2020 for persistent hypercalcaemia on background parathyroidectomy 2011 primary hyperparathyroidism (PHPT), while she admitted local...

10.1530/edm-24-0004 article EN cc-by-nc-nd Endocrinology Diabetes and Metabolism Case Reports 2024-07-01

Prolactinomas are the most common hypersecretory pituitary adenoma. The traditional first-line therapy is dopamine agonists (DAs), which highly effective and tolerated in majority of cases. However, DAs have potential for psychiatric complications, such as psychosis, impulse control disorders anxiety/depression. It has been repeatedly suggested that aripiprazole may be considered individuals with a disorder prolactinoma, potentially enabling DA dose reduction or even cessation. We report...

10.1530/eo-24-0065 article EN cc-by-nc-nd Endocrine Oncology 2024-12-19

Abstract Disclosure: E. Mignone: None. K. Neal: Background: Multiple Endocrine Neoplasia type 1 (MEN1) is a rare and under recognised syndrome. It has not been previously reported in Indigenous Australians for this reason. Clinical Case: A 48-year-old Australian female was consulted on by an inpatient endocrine team March 2020 persistent hypercalcaemia background of parathyroidectomy 2011 primary hyperparathyroidism (PHPTH). She admitted to remote hospital investigation management acute...

10.1210/jendso/bvad114.1343 article EN cc-by-nc-nd Journal of the Endocrine Society 2023-10-01
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