A5021257420- Advanced X-ray Imaging Techniques
- Cardiac Imaging and Diagnostics
- Advanced Optical Network Technologies
- Particle Accelerators and Free-Electron Lasers
- Software-Defined Networks and 5G
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced Electron Microscopy Techniques and Applications
- Takotsubo Cardiomyopathy and Associated Phenomena
- Network Traffic and Congestion Control
- Cardiac electrophysiology and arrhythmias
- Optical Network Technologies
- Cardiac Arrest and Resuscitation
- Advanced Photonic Communication Systems
- Laser-Plasma Interactions and Diagnostics
- Microbial Metabolic Engineering and Bioproduction
- Crystallography and Radiation Phenomena
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Mobile Agent-Based Network Management
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Scheduling and Optimization Algorithms
- Cyclone Separators and Fluid Dynamics
RIKEN
1980-2025
SPring-8
2016-2025
Universität Hamburg
2025
Osaka National Hospital
2024
Tohoku University Hospital
2023
Japan Synchrotron Radiation Research Institute
2018-2023
The University of Tokyo
1991-2021
Rikkyo University
2018
Rosatom (Russia)
2018
Russian Academy of Sciences
2018
Extracorporeal membrane oxygenation (ECMO) and percutaneous coronary intervention (PCI) may be useful in cardiopulmonary resuscitation. However, little is known about the combination of ECMO intra-arrest PCI. This study investigated efficacy rapid-response PCI patients with cardiac arrest complicated by acute syndrome who were unresponsive to conventional resuscitation.This multicenter cohort was conducted use database Hiroshima City, Japan. Between January 2004 May 2011, performed 86 CPR....
Background The time course of the electrocardiographic (ECG) changes in patients with tako-tsubo syndrome remains unknown. Methods and Results In present study, 16 15 anterior acute myocardial infarction minimal enzymatic release (minimal AMI) were evaluated. Left ventricular dysfunction dramatically resolved approximately 2 weeks later both groups. syndrome, admission ECG usually showed ST segment elevation, especially leads V3-6. T wave inversion deepened progressively to its first...
Significance Understanding ultraintense light–matter interactions is an intriguing subject from viewpoints of basic science and practical applications. For the X-ray region, such research fields have opened up with emergence free-electron lasers (XFELs). By using X-ray–X-ray pump–probe scheme, we firstly measured atomic response to XFEL light femtosecond–ångstrom time–space resolutions. It was found that position freezing until 20 fs after irradiation, which supports feasibility damageless...
Structure analysis of small crystals is important in areas ranging from synthetic organic chemistry to pharmaceutical and material sciences, as many compounds do not yield large crystals. Here we present the detailed characterization structure an molecule, rhodamine-6G, determined at a resolution 0.82 Å by X-ray free-electron laser (XFEL). Direct comparison this with that obtained electron crystallography same sample batch microcrystals shows both methods can accurately distinguish position...
Here, we systematically investigated the effects of thiophene-fused isomer and end-cap substitution on high-layered crystallinity, film formability, field-effect transistor characteristics in π-extended alkylated organic semiconductors (OSCs). We developed four kinds unsymmetric rod-like OSCs based syn-/anti-isomers benzothieno[6,5-b]-/benzothieno[5,6-b]-benzothieno[3,2-b]thiophene (BTBTT) with phenyl/alkyl substitutions different alkyl chain lengths: synCn antiCn (n = 6, 10). The layered...
Earlier studies have often required the absence of obstructive coronary artery disease (CAD) as criteria. However, it is probable that patients with tako-tsubo cardiomyopathy an incidental CAD because most are elderly. We assessed prevalence CAD.We reviewed angiograms 97 Japanese cardiomyopathy. A wrapped left anterior descending (LAD) was defined a LAD perfused at least one-quarter inferior wall ventricle in 30 degrees right oblique projection.Ten (10%) had definitively greater than 75%...
A method of fabricating multilayer focusing mirrors that can focus X-rays down to 10 nm or less was established in this study. The wavefront aberration induced by Kirkpatrick-Baez mirror optics measured using a single grating interferometer at photon energy 9.1 keV SPring-8 Angstrom Compact Free Electron Laser (SACLA), and the shape then directly corrected employing differential deposition method. accuracies these processes were carefully investigated, considering accuracy required for...
There is a growing demand for structure determination from small crystals, and the three-dimensional electron diffraction (3D ED) technique can be employed this purpose. However, 3D ED has certain limitations related to crystal thickness data quality. We here present application of serial X-ray crystallography (SX) with free lasers (XFELs) (a few μm or less) thin hundred nm crystals novel compounds dispersed on substrate. For XFEL exposures, two-dimensional (2D) scanning substrate coupled...
To investigate whether admission hyperglycaemia in non-diabetic patients with acute myocardial infarction (AMI) is a surrogate for previously undiagnosed abnormal glucose tolerance.Two hundred AMI were divided into three groups: 81 < 7.8 mmol/L (group 1), 83 > or = and 11.1 2), 36 3). Abnormal tolerance, diabetes, impaired tolerance (IGT) was diagnosed by oral test (OGTT). OGTT identified diabetes 53 (27%) IGT 78 (39%). When the fasting criteria applied, however, only 14 (7%) as having...
X-ray two-photon absorption (TPA) spectrum of metallic copper is measured using a free-electron laser (XFEL). The differs from that by the conventional one-photon (OPA), and characterized peak below Fermi level, which assigned to transition 3d state. impact XFEL pulse on OPA discussed analyzing pulse-energy dependence, indicates intrinsic TPA measured.
Ultrafast changes of charge density distribution in diamond after irradiation with an intense x-ray pulse (photon energy, 7.8 keV; duration, 6 fs; intensity, $3\ifmmode\times\else\texttimes\fi{}{10}^{19}\text{ }\text{ }\mathrm{W}/{\mathrm{cm}}^{2}$) have been visualized the pump--x-ray probe technique. The measurement reveals that covalent bonds are broken and electron around each atom becomes almost isotropic within $\ensuremath{\sim}5\text{ }\mathrm{fs}$ intensity maximum pump pulse. 15 fs...
In resistance spot welding (RSW) of Fe and Al alloy, an intermetallic compound (IMC) is formed at the joining interface, it known that strength joint decreases as IMC becomes thicker. One factors determines thickness temperature field during welding, which considered to vary greatly depending on convection within alloy melting zone. Therefore, changes in are possibly affect state formation, but there have been few detailed studies this phenomenon. study, zone Fe-Al RSW was varied effect...
Recent studies have demonstrated that stress-induced Tako-tsubo cardiomyopathy is likely to occur in elderly female patients.The purpose of this study was evaluate gender differences the clinical characteristics patients with cardiomyopathy.This consisted 102 cardiomyopathy. It characterized by akinesia/hypokinesia mid-to-distal portion left ventricular chamber, normokinesia/hyperkinesia basal an ejection fraction less than 50% on transthoracic echocardiography.There were 13 male and 89...
Heme oxygenase 1 (HO-1) is rapidly induced by stress, degrading pro-oxidant heme into carbon monoxide, bilirubin, and free iron (Fe). Induction of HO-1 an important defense mechanism against tissue injury. Here, we tested the hypothesis that activated in myocardium after acute myocardial infarction (AMI) humans.Changes activity AMI were analyzed measuring serum levels bilirubin Fe. Blood samples collected patients with (n = 41) serially interventional therapy compared non-AMI subjects 18)....
X-ray diffraction of silicon irradiated with tightly focused femtosecond x-ray pulses (photon energy, 11.5 keV; pulse duration, 6 fs) was measured at various intensities up to 4.6×10^{19} W/cm^{2}. The measurement reveals that the intensity is highly suppressed when reaches order 10^{19} With a dedicated simulation, we confirm observed reduction can be attributed change in individual atomic scattering factors due ultrafast creation ionized atoms through photoionization, Auger decay, and...
A 74-year-old woman with hypertension and bronchial asthma had chest discomfort at rest 4 days later was admitted to her nearby hospital because of the sudden onset right hemiparesis. The hemiparesis almost disappeared within 24 h onset, but an electrocardiogram showed sinus tachycardia diffuse symmetrical T-wave inversion, she referred for cardiac examination. Coronary angiography did not reveal any significant coronary artery stenosis, left ventriculography revealed severe hypokinesis...
Ascospore formation in yeast is accomplished through a cell division which daughter nuclei are engulfed by newly formed plasma membranes, termed prospore membranes. Closure of the membrane must be coordinated with end meiosis II to ensure proper division. AMA1 encodes meiosis-specific activator anaphase promoting complex (APC). The activity APC(Ama1) inhibited before II, but substrates specifically targeted for degradation Ama1 at unknown. We show here that ama1Delta mutants defective...