A5016171849- Cannabis and Cannabinoid Research
- Neuroscience and Neuropharmacology Research
- Pain Mechanisms and Treatments
- Adenosine and Purinergic Signaling
- Natural product bioactivities and synthesis
- Pharmacological Receptor Mechanisms and Effects
- Endoplasmic Reticulum Stress and Disease
- Sesquiterpenes and Asteraceae Studies
- Nerve injury and regeneration
- Mitochondrial Function and Pathology
- Plant biochemistry and biosynthesis
- Neurotransmitter Receptor Influence on Behavior
- Synthesis and Reactions of Organic Compounds
University of Arizona
2023-2025
Terpenes are small hydrocarbon compounds that impart aroma and taste to many plants, including Cannabis sativa . A number of studies have shown terpenes can produce pain relief in various states both humans animals. However, these were methodologically limited few established mechanisms action. In our previous work, we showed the geraniol, linalool, β-pinene, α-humulene, β-caryophyllene produced cannabimimetic behavioral effects via multiple receptor targets. We thus expanded this work...
Chronic pain conditions affect nearly 20% of the population in United States. Current medical interventions, such as opioid drugs, are effective at relieving but accompanied by many undesirable side effects. This is one reason increased numbers chronic patients have been turning to Cannabis for management. contains bioactive chemical compounds; however, current research looking into lesser-studied minor cannabinoids lacks uniformity between experimental groups and/or excludes female mice...
Abstract Terpenes are small hydrocarbon compounds that impart aroma and taste to many plants, including Cannabis sativa . A number of studies have shown terpenes can produce pain relief in various states both humans animals. However, these were methodologically limited few established mechanisms action. In our previous work, we showed the geraniol, linalool, β-pinene, α- humulene, β-caryophyllene produced cannabimimetic behavioral effects via multiple receptor targets. We thus expanded this...