Afsar Ali

ORCID: 0009-0008-5419-1777
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Research Areas
  • Vibrio bacteria research studies
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Aquaculture disease management and microbiota
  • Crystallography and molecular interactions
  • Salmonella and Campylobacter epidemiology
  • Metal complexes synthesis and properties
  • Bacterial biofilms and quorum sensing
  • Electrocatalysts for Energy Conversion
  • Metal-Organic Frameworks: Synthesis and Applications
  • Bacteriophages and microbial interactions
  • Escherichia coli research studies
  • Antibiotic Resistance in Bacteria
  • Child Nutrition and Water Access
  • COVID-19 epidemiological studies
  • Advanced battery technologies research
  • Fecal contamination and water quality
  • Data-Driven Disease Surveillance
  • Yersinia bacterium, plague, ectoparasites research
  • Magnetism in coordination complexes
  • Synthesis and Characterization of Heterocyclic Compounds
  • Cassava research and cyanide
  • CO2 Reduction Techniques and Catalysts
  • Identification and Quantification in Food
  • Parasitic infections in humans and animals

University of Florida
2016-2025

Indian Institute of Technology Delhi
2007-2025

University of Louisiana at Lafayette
2025

Sharda University
2023-2024

University of Engineering and Technology Taxila
2024

Indian Institute of Technology Gandhinagar
2019-2024

University of Engineering and Technology Lahore
2024

University of Kalyani
2023

University of Lahore
2022-2023

Florida College
2014-2023

ABSTRACT The complete genome of Aeromonas hydrophila ATCC 7966 T was sequenced. , a ubiquitous waterborne bacterium, has been placed by the Environmental Protection Agency on Contaminant Candidate List because its potential to cause human disease. 4.7-Mb this emerging pathogen shows physiologically adroit organism with broad metabolic capabilities and considerable virulence potential. A large array genes, including some identified in clinical isolates spp. or Vibrio spp., may confer upon...

10.1128/jb.00621-06 article EN Journal of Bacteriology 2006-11-16

The occurrence of outbreaks cholera in Africa 1970 and Latin America 1991, mainly coastal communities, the appearance new serotype Vibrio cholerae O139 India subsequently Bangladesh have stimulated efforts to understand environmental factors influencing growth geographic distribution epidemic serotypes. Because severity recent epidemics, is now being considered by some infectious disease investigators as a "reemerging" disease, prompting work on ecology vibrios. Epidemiological ecological...

10.1128/aem.71.8.4645-4654.2005 article EN Applied and Environmental Microbiology 2005-08-01

Vibrio cholerae O1 in plankton samples collected from ponds and rivers between February 1987 January 1990 Matlab, Bangladesh, was detected by the fluorescent-monoclonal antibody (FA) technique. Samples were at sites which monitored fortnightly (fixed sites) as well that part of a case-control study. FA results compared with those obtained conventional culture methods (CM). A total 876 collected; V. 563 (64.27%) method 3 (0.34%) CM. Of fixed-site samples, 439 (63.62%) positive none 93 case...

10.1128/aem.56.8.2370-2373.1990 article EN Applied and Environmental Microbiology 1990-08-01

How Vibrio cholerae spreads around the world and what determines its seasonal peaks in endemic areas are not known. These features of cholera have been hypothesized to be primarily result environmental factors associated with aquatic habitats that can now identified. Since 1997, fortnightly surveillance 4 widely separated geographic locations Bangladesh has performed identify patients collect data. A total 5670 (53% <5 years age) studied; 14.3% had (10.4% due V. O1 El Tor, 3.8% O139). Both...

10.1086/345865 article EN The Journal of Infectious Diseases 2002-12-17

ABSTRACT Toxigenic Vibrio cholerae , rarely isolated from the aquatic environment between cholera epidemics, can be detected in what is now understood to a dormant stage, i.e., viable but nonculturable when standard bacteriological methods are used. In research reported here, biofilms have proved source of culturable V. even nonepidemic periods. Biweekly environmental surveillance for was carried out Mathbaria, an area endemicity adjacent Bay Bengal, with focus on O1 and O139 Bengal. A total...

10.1128/aem.72.4.2849-2855.2006 article EN Applied and Environmental Microbiology 2006-04-01

Novel preventatives could help in efforts to limit Vibrio cholerae infection and the spread of cholera. Bacteriophage (phage) treatment has been proposed as an alternative intervention, given rapid replication virulent phages, prey specificity, relative ease finding new phages. Phage tropism is dictated part by presence phage receptors on bacterial surface. While many phages that can kill V. have isolated, whether this pathogen able defend itself neutralizing binding unknown. Here, we show...

10.1128/jb.00792-17 article EN Journal of Bacteriology 2018-04-17

Rising populations and industrial expansion necessitate sustainable alternatives to conventional cement-based concrete. Geopolymers, with their impressive mechanical properties, eco-friendliness, potential for waste utilization, offer a promising solution. Yet, concerns like rapid setting low workability limit widespread adoption. This study addresses these challenges by optimizing geopolymer concrete incorporating ground granulated blast furnace slag (GGBS) blended bentonite dolomite...

10.1016/j.asej.2024.102708 article EN cc-by-nc-nd Ain Shams Engineering Journal 2024-03-05

Abstract Within concrete engineering, the uptake of self-compacting (SCC) represents a notable trend, delivering improved workability and placement efficiency. However, challenges persist, notably in achieving optimal performance while mitigating environmental impacts, particularly cement consumption. simply reducing content mix design can directly compromise structural-concrete requirements. Towards these challenges, global trends emphasize utilization appropriate waste materials blended...

10.1038/s41598-024-62499-w article EN cc-by Scientific Reports 2024-05-29

Virulence of Vibrio cholerae depends on secretion cholera toxin (CT), which is encoded within the genome a filamentous phage, CTXφ. Release CT mediated by extracellular protein (eps) type II system. Here, outer membrane component this system, EpsD, was shown to be required for phage as well. Thus, EpsD plays role both in pathogenicity and horizontal transfer key virulence gene. Genomic analysis suggests that additional phages also exploit chromosome-encoded channels.

10.1126/science.288.5464.333 article EN Science 2000-04-14

Vibrio cholerae can switch to a 'rugose' phenotype characterized by an exopolysaccharide (EPS) matrix, wrinkled colony morphology, increased biofilm formation and survival under specific conditions. The vps gene cluster responsible for the biosynthesis of rugose EPS (rEPS) is positively regulated VpsR. We recently identified media (APW#3) promoting production found epidemic strains at higher frequency than non-pathogenic strains, suggesting this are important in cholera epidemiology. In...

10.1016/s0378-1097(03)00657-8 article EN FEMS Microbiology Letters 2003-09-16

The present work shows that the Co3+ coordination to deprotonated pyridine-amide ligands orients noncoordinated or hanging pyridine rings, thus furnishing a cleft in which Zn2+ ions coordinate. building block approach points out strategy incorporate Lewis acidic metal center periphery. This has been used synthesize Co3+-centered−Zn2+-peripheral heterobimetallic complexes. These complexes have thoroughly characterized including structural studies and successfully shown catalyze Beckmann...

10.1021/ic7016424 article EN Inorganic Chemistry 2007-12-12

Altered El Tor Vibrio cholerae O1, with classical cholera toxin B gene, was isolated from 16 patients severe diarrhea at St. Mark's Hospital, Arbonite, Haiti, <3 weeks after onset of the current epidemic. Variable-number tandem-repeat typing 187 isolates showed minimal diversity, consistent a point source for

10.3201/eid1704.101973 article EN cc-by Emerging infectious diseases 2011-03-04

In response to antibiotic and/or environmental stress, some species of bacteria shift a "persister" phenotype. Although toxigenic Vibrio cholerae, responsible for the disease cholera, can be found in nutrient-poor aquatic environments endemic areas, underlying mechanism(s) by which culturable cells persist these reservoirs is largely unknown. Here we report that introduction V. cholerae into filter sterilized lake water (FSLW) microcosm promoted what have defined as phenotype (PP) was >700...

10.1371/journal.pone.0045187 article EN cc-by PLoS ONE 2012-09-18

An epidemic of cholera infections was documented in Haiti for the first time more than 100 years during October 2010. Cases have continued to occur, raising question whether microorganism has established environmental reservoirs Haiti. We monitored 14 sites near towns Gressier and Leogane April 2012-March 2013. Toxigenic Vibrio cholerae O1 El Tor biotype strains were isolated from 3 (1.7%) 179 water samples; nontoxigenic V. an additional samples. All samples containing also contained non-O1...

10.3201/eid2003.131293 article EN cc-by Emerging infectious diseases 2014-01-22

The spread of cholera in the midst an epidemic is largely driven by direct transmission from person to person, although it well-recognized that Vibrio cholerae also capable growth and long-term survival aquatic ecosystems. While prior studies have shown reservoirs are important persistence disease on Indian subcontinent, epidemiological view postulating locally evolving environmental V. contributes outbreaks outside Asia remains debated. single-source introduction toxigenic O1 Haiti, one...

10.1073/pnas.1918763117 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2020-03-30

The development of a bidirectional catalyst for oxygen reduction and water oxidation is the key to establishing sustainable energy transduction from renewable resources. We report stable homogeneous molecular copper complex, comprising labile diimine-dioxime ligand framework, that enables rapid complete 4e–/4H+ electrocatalysis both (2.1(±0.01) × 105 s–1) (3.2(±0.01) in aqueous solution presumably via situ formation binuclear intermediates. Computational investigations unravel pivotal role...

10.1021/acscatal.1c01542 article EN ACS Catalysis 2021-04-29

Gold- and silver-based plasmonic materials have emerged as game changers in the field of solar-driven small-molecule activation because their enhanced broadly tunable absorption cross sections. This review essays cutting-edge research plasmon-mediated while highlighting role nanostructures photosensitizers, leading to advent numerous photocatalytic materials. Here we initiate discussion with a basic overview optical properties, followed by detailed analysis three major categories...

10.1021/acscatal.1c05245 article EN ACS Catalysis 2022-01-04

Controlling the selectivity of 4e–/4H+ reduction oxygen over 2e–/2H+ is a key challenge in making efficient catalysts for fuel cell cathodes. A tyrosine residue poised active site cytochrome c oxidase (CcO) has been demonstrated to control hydrogen atom transfer reactions and cleavage O–O bond Fe–O–O–Cu moiety yield water. In couple small-molecule iron complexes supported by porphyrin derivatives, it was shown that presence protonation sites at secondary coordination sphere plays an...

10.1021/acscatal.3c00822 article EN ACS Catalysis 2023-04-04

The present work demonstrates the utilization of Co(3+) complex pyridine-amide ligand as building blocks for assembly heterobimetallic complexes. These Co(3+)-centered orient tethered pyridine groups to a preorganized cleft that successively coordinates Cd(2+) and Hg(2+) ions in periphery. Both {Cd(2+)-Co(3+)-Cd(2+)} {Hg(2+)-Co(3+)-Hg(2+)} complexes have been thoroughly characterized, including crystal structures depicting interesting weak interactions solid state. further used catalytic...

10.1021/ic900223f article EN Inorganic Chemistry 2009-05-15

Two {Co(3+)-Zn(2+)} heterobimetallic coordination networks have been synthesized utilizing Co(3+) complex as the building blocks. The structural studies reveal 2D sheet-like where containing blocks are connected through Zn(2+) ions. different generate two unique evidenced by crystallographic and other properties. These shown to catalyze Lewis metal ion assisted Strecker reaction in heterogeneous manner.

10.1039/c0dt00511h article EN Dalton Transactions 2010-01-01

This work shows the syntheses, structures, and hydrogen-bonding based self-assembly of Co3+ coordination complexes containing appended phenol catechol groups. Placement hydrogen-bond donors (in O–H groups catechol) acceptors C═Oamide groups) in a single molecule results complementary yet unique self-assembly.

10.1021/cg201369g article EN Crystal Growth & Design 2012-01-04

Since the identification of first cholera case in 2010, disease has spread epidemic form throughout island nation Haiti; as 2014, about 700,000 cases have been reported, with over 8,000 deaths. While numbers declined, more fundamental question whether causative bacterium, Vibrio cholerae established an environmental reservoir surface waters Haiti remains to be elucidated. In a previous study conducted between April 2012 and March 2013, we reported isolation toxigenic V. O1 from Ouest...

10.1371/journal.pone.0124098 article EN cc-by PLoS ONE 2015-04-08
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