A5055415156- Barrier Structure and Function Studies
- Ion Transport and Channel Regulation
- Neuroinflammation and Neurodegeneration Mechanisms
- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
- Acute Ischemic Stroke Management
- Ion Channels and Receptors
- Olfactory and Sensory Function Studies
Australian Regenerative Medicine Institute
2021-2024
Monash University
2021-2024
The photothrombotic stroke model relies on the interaction between photosensitive-dye and light for clot formation. Interestingly, relationship length of exposure stroke-outcome has never been examined. This yet to be established in FVB/N strain, even though stroke-outcomes are strain-specific. Therefore, this study aimed examine effect different lengths two strains mice stroke. Male C57Bl/6 were subjected using 15, 18, or 20-min exposure. Mice underwent functional testing up 7 days. Infarct...
Activation of acid-sensing ion channel 1a (ASIC1a) plays a major role in mediating acidosis-induced neuronal injury following stroke. Therefore, the inhibition ASIC1a is potential therapeutic avenue for treatment Venom-peptide Hi1a, selective and highly potent inhibitor, reduces infarct size functional deficits when injected into brain after stroke rodents. However, its efficacy administered using clinically relevant route administration remains to be established. current investigation aims...
Abstract The photothrombotic stroke model relies on the interaction between photosensitive-dye and light for clot formation. Interestingly, relationship length of exposure stroke-outcome has never been examined. This yet to be established in FVB/N strain, even though stroke-outcomes are strain-specific. Therefore, this study aimed examine effect different lengths two strains mice stroke. Male C57Bl/6 were subjected using 15, 18, or 20-mins exposure. Mice underwent functional testing up 7...