A5084968531- Diamond and Carbon-based Materials Research
- Electronic and Structural Properties of Oxides
- Cancer-related molecular mechanisms research
- Semiconductor materials and devices
- High-pressure geophysics and materials
- interferon and immune responses
- Hippo pathway signaling and YAP/TAZ
Guangzhou Eighth People's Hospital
2024
Guangzhou Medical University
2024
Harbin Institute of Technology
2022-2023
Physiologically, FoxA1 plays a key role in liver differentiation and development, pathologically exhibits an oncogenic prostate breast cancers. However, its upstream regulation tumorigenesis remain unclear. Here, we demonstrate that acts as tumor suppressor cancer. Using CRISPR-based kinome screening approach, noncanonical inflammatory kinase IKBKE has been identified to inhibit transcriptional activity. Notably, directly binds phosphorylates reduce complex formation DNA interaction, leading...