A5043052596- Aging, Health, and Disability
- Breastfeeding Practices and Influences
- Education and Labor Relations
- Nursing care and research
- Health and Lifestyle Studies
- Retirement, Disability, and Employment
- Hepatitis B Virus Studies
- Palliative and Oncologic Care
- Amino Acid Enzymes and Metabolism
- Tendon Structure and Treatment
- Social Sciences and Policies
- HIV/AIDS drug development and treatment
- Palliative Care and End-of-Life Issues
- Employment, Labor, and Gender Studies
- Hepatitis C virus research
- Neurological diseases and metabolism
- Osteoarthritis Treatment and Mechanisms
- Ethics and bioethics in healthcare
- Prion Diseases and Protein Misfolding
- Knee injuries and reconstruction techniques
The University of Texas Health Science Center at Houston
2025
Objective.The aim of this study was to develop a genetic prognostic tool predict radiographic progression towards severe disease in primary knee OA (KOA) patients.Methods.This investigation cross-sectional, retrospective, multicentric association 595 Spanish KOA patients.Caucasian patients aged 540 years at the time diagnosis KellgrenLawrence grade 2 or 3 were included.Patients who progressed score 4 referred for total replacement within 8 after classified as progressors disease.Clinical...
ABSTRACT Alzheimer's disease (AD) is a complex neurodegenerative proteinopathy in which Aβ and tau misfold aggregate into entities that structurally unsettle native proteins, mimicking prion‐like or “seeding” process. These “seeds” can arrange different conformations strains might display distinct pathogenic properties. Furthermore, recent evidence suggests microglia play key role the amyloidogenic event modulate propagation aggregation processes. Here, we employed histological molecular...