A5101850957- SARS-CoV-2 and COVID-19 Research
- Vitamin C and Antioxidants Research
- Neurological Disease Mechanisms and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Food Quality and Safety Studies
- Melanoma and MAPK Pathways
- Vitamin D Research Studies
- Cancer Immunotherapy and Biomarkers
- Case Reports on Hematomas
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Cutaneous Melanoma Detection and Management
- Biochemical effects in animals
- Gout, Hyperuricemia, Uric Acid
- Spondyloarthritis Studies and Treatments
Fifth Tianjin Central Hospital
2023-2024
Chinese Academy of Agricultural Sciences
2023
A retrospective cross-sectional study using data from an outpatient clinic in China was conducted to investigate the clinical features of early-onset gout patients. All patients diagnosed with were asked about characteristics their and comorbid diseases. Patients presenting acute flares common triggers before flare. "Early-onset" defined as onset 40 years "late-onset" ≥40 years. Major joint involvement, flare frequency presentation, cumulative number involved joints, proportions tophi...
Vaccination has proven effective against SARS-CoV-2 infection but vaccines were originally based on the wild type and emerging variants have led to a decrease in protective efficacy. There is an urgent need for broad-spectrum vaccine protection variants. A Delta strain spike protein was created by optimization of vector, codon, structure produce subunit immunogen (Delta-6P-S) containing six proline mutations, stable pre-fusion conformation, with high expression CHO-S cells. Immunogenicity...