Tiffany Chang

ORCID: 0009-0008-7751-8429
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About
Contact & Profiles
Research Areas
  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Cutaneous lymphoproliferative disorders research
  • CAR-T cell therapy research
  • Viral-associated cancers and disorders
  • Lung Cancer Treatments and Mutations
  • Autoimmune and Inflammatory Disorders Research
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Mental Health Research Topics
  • Functional Brain Connectivity Studies
  • CNS Lymphoma Diagnosis and Treatment
  • EEG and Brain-Computer Interfaces
  • Adolescent and Pediatric Healthcare
  • T-cell and Retrovirus Studies
  • Cancer Genomics and Diagnostics
  • Cancer-related gene regulation
  • Cancer Immunotherapy and Biomarkers
  • Toxin Mechanisms and Immunotoxins
  • Immunodeficiency and Autoimmune Disorders
  • Immune Cell Function and Interaction
  • Body Image and Dysmorphia Studies
  • Neuroscience and Music Perception
  • Psychedelics and Drug Studies
  • Radiopharmaceutical Chemistry and Applications
  • Epigenetics and DNA Methylation

Kettering University
2023-2024

Memorial Sloan Kettering Cancer Center
2022-2024

Shanghai Medical College of Fudan University
2021-2022

Nathan Kline Institute for Psychiatric Research
2016

Nodal peripheral T-cell lymphomas (PTCL), the most common PTCLs, are generally treated with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP)-based curative-intent chemotherapy. Recent molecular data have assisted in prognosticating these but reports lack detailed baseline clinical characteristics treatment courses. We retrospectively evaluated cases of PTCL CHOP-based chemotherapy that had tumors sequenced by Memorial Sloan Kettering Integrated Mutational Profiling...

10.1182/bloodadvances.2023009953 article EN cc-by-nc-nd Blood Advances 2023-04-20

Gene fusions involving tumor protein p63 gene (TP63) occur in multiple T and B cell lymphomas portend a dismal prognosis for patients. The function mechanisms of TP63 remain unclear, there is no target therapy patients with lymphoma harboring fusions. Here, we show that act as bona fide oncogenes are essential fusion-positive lymphomas. Transgenic mice expressing TBL1XR1::TP63, the most common fusion, develop diverse recapitulate human identify coordinate recruitment two epigenetic modifying...

10.1126/scitranslmed.adi7244 article EN Science Translational Medicine 2023-09-20

The sense of 'Attention' has a certain degree influence on the effectiveness learning. It was found that good music boosts reading interest. Music referral systems have been proactively explored using hybrid methods. In this work, first, select electroencephalographic(EEG) used to record and review attention according individual's choices for material due introduction an device. Then, collected brainwave data values are filtered invalid then combined with Supper Vector Machine (SVM)...

10.1109/icairc52191.2021.9544927 article EN 2021-06-25

Abstract This data descriptor describes a repository of openly shared from an experiment to assess inter-individual differences in default mode network (DMN) activity. includes cross-sectional functional magnetic resonance imaging (fMRI) the Multi Source Interference Task, DMN deactivation, Moral Dilemma activation, resting state fMRI scan, and neurofeedback paradigm, modulation, along with accompanying behavioral cognitive measures. We report technical validation n=125 participants final...

10.1101/075275 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2016-09-15

Abstract Recurrent chromosomal rearrangements are a hallmark of hematologic malignancies and play critical roles in pathogenesis. The TP53 analog TP63 is rearranged 5-10% diverse subtypes both aggressive T- B-cell lymphomas. Patients with TP63-rearranged lymphomas have dismal outcomes, 5-year overall survival rates between 0-17%, depending on cohorts. function mechanisms fusion proteins tumorigenesis poorly understood. As result, attempts to treat these patients date been largely empiric....

10.1158/1538-7445.am2023-5755 article EN Cancer Research 2023-04-04

Olfactory reference syndrome (ORS) is a delusion in which person believes that he or she exudes displeasing body aroma others perceive negatively. The axilla has been reported as single primary source only one patient. Furthermore, ORS rarely to be associated with food odor. In these instances, the not edible. Delusions of presenting alliaceous edible aromas have heretofore described.One week after undergoing catheter ablation for atrial fibrillation, this 42-year-old right-handed male...

10.1017/s109285292200027x article EN CNS Spectrums 2022-04-01
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