A5021709456- Renal cell carcinoma treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Ultrasound and Hyperthermia Applications
- Renal and related cancers
- Medical Imaging and Pathology Studies
- Colorectal Cancer Screening and Detection
- Ultrasound Imaging and Elastography
- Radiation Dose and Imaging
- Bladder and Urothelial Cancer Treatments
- Advanced X-ray and CT Imaging
- Lung Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- MRI in cancer diagnosis
- Radiology practices and education
- Neuroendocrine Tumor Research Advances
- Gastric Cancer Management and Outcomes
- Pediatric Urology and Nephrology Studies
- Colorectal Cancer Surgical Treatments
- Genetic and Kidney Cyst Diseases
- Radiomics and Machine Learning in Medical Imaging
- Genetic factors in colorectal cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ultrasonics and Acoustic Wave Propagation
- Advanced Radiotherapy Techniques
University of Wisconsin–Madison
2016-2025
UW Health University Hospital
2008-2025
Cleveland Clinic Lerner College of Medicine
2024
Highland Community College - Illinois
2012-2023
Madison Group (United States)
2011-2019
University of Wisconsin Foundation
2017
Wisconsin Division of Public Health
2017
Wisconsin Institutes for Discovery
2015
University of Wisconsin–Milwaukee
2014-2015
University Radiology
2013
Advanced neoplasia represents the primary target for colorectal-cancer screening and prevention. We compared diagnostic yield from parallel computed tomographic colonography (CTC) optical colonoscopy (OC) programs.We CTC in 3120 consecutive adults (mean [+/-SD] age, 57.0+/-7.2 years) with OC 3163 58.1+/-7.8 years). The main outcome measures included detection of advanced (advanced adenomas carcinomas) total number harvested polyps. Referral polypectomy during was offered all CTC-detected...
Image-guided thermal ablation is an evolving and growing treatment option for patients with malignant disease of multiple organ systems. Treatment indications have been expanding to include benign tumors as well. Specifically, the most prevalent date in liver (primary metastatic disease, well such hemangiomas adenomas), kidney (primarily renal cell carcinoma, but also angiomyolipomas oncocytomas), lung disease), soft tissue and/or bone osteoid osteomas). Each system has different underlying...
The purpose of this study was to investigate the prevalence hepatic steatosis in an asymptomatic U.S. adult population using attenuation values at unenhanced CT as reference standard. We also assessed utility known clinical risk factors for diagnosis.For 3,357 consecutive adults (1,865 women and 1,492 men; mean age, 57.0 years), splenic (Hounsfield units) were obtained by a low-dose colonography technique colorectal cancer screening. Multiple criteria applied, including liver thresholds...
To evaluate the frequency and estimated costs of additional diagnostic workup for extracolonic findings detected at computed tomographic (CT) colonography in a large screening cohort.This retrospective HIPAA-compliant study, which had institutional review board approval, evaluated 2195 consecutive asymptomatic adults (1199 women, 996 men; age range, 40-90 years; mean age, 58.0 years +/- 8.1 [standard deviation]) undergoing low-dose CT colonographic performed without contrast material single...
Purpose: To compare the performance of equivalently sized radiofrequency and microwave ablation applicators in a normal porcine lung model. Materials Methods: All experiments were approved by an institutional animal care use committee. A total 18 ablations performed vivo lungs. By using computed tomographic (CT) fluoroscopic guidance, 17-gauge cooled triaxial antenna (n = 9) (RF) electrode placed percutaneously. Ablations for 10 minutes either 125 W power or 200 RF delivered with...
Preoperative Pulmonary Nodule Localization: A Comparison of Methylene Blue and Hookwire TechniquesMark Kleedehn1, David H. Kim1, Fred T. Lee, Jr.1,2, Meghan G. Lubner1, Jessica B. Robbins1, Timothy J. Ziemlewicz1 Louis Hinshaw1,3Audio Available | Share Claim CREDIT
Disparate results from the existing large CT colonography (CTC) trials suggest that 2D polyp detection is less sensitive than 3D detection, but no direct evidence exists to support this claim. Our goal was assess sensitivity of primary with cases Department Defense CTC screening trial and compare evaluation previous trials.Ten radiologists, blinded findings, retrospectively interpreted 730 consecutive colonoscopy-proven in asymptomatic adults using a approach, reserved for problem solving....
To assess the effect of using computer-aided detection (CAD) in second-read mode on readers' accuracy interpreting computed tomographic (CT) colonographic images.The contributing institutions performed examinations under approval their local institutional review board, with waiver informed consent, for this HIPAA-compliant study. A cohort 100 colonoscopy-proved cases was used: In 52 patients findings positive polyps, 74 polyps 6 mm or larger were observed 65 colonic segments; 48 negative no...
Few long-term data describe the natural history of hepatic hemangiomas. Because these lesions are frequently imaged repetitively on studies performed for other indications, health care professionals commonly confronted with problem a growing hemangioma. rate and magnitude normal growth is not well characterized, it difficult to recognize at an abnormal rate, which may require further evaluation or intervention.To establish quantitatively expected hemangiomas define measure hemangioma that...
Purpose To compare microwave ablation zones created by using sequential or simultaneous power delivery in ex vivo and liver tissue. Materials Methods All procedures were approved the institutional animal care use committee. Microwave ablations performed both models with a 2.45-GHz system capable of powering up to three antennas simultaneously. Two- three-antenna arrays evaluated each model. Sequential delivering (50 W vivo, 65 vivo) for 5 minutes per antenna (10 15 total time ablations,...
Purpose To evaluate the effects of tumor complexity and technique on early midterm oncologic efficacy rate complications for 100 consecutive biopsy-proved stage T1a renal cell carcinomas (RCCs) treated with percutaneous microwave ablation. Materials Methods This HIPAA-compliant, single-center retrospective study was approved by institutional review board. The requirement to obtain informed consent waived. Ninety-six patients (68 men, 28 women; mean age, 66 years ± 9.4) N0M0 RCCs (median...
The purpose of this study was to compare efficacy and safety biopsy guided by ultrasound (US) versus CT for lung lesions with pleural contact.Among 1269 image-guided thoracic biopsies obtained at our institution between 2004 2016, 150 were US-guided contact (78 men, 72 women; mean age, 67 years). Of those, 94 performed using US only; 56 had initial localization. A comparison cohort 100 consecutive CT-guided identified (60 40 65 Biopsy type, number passes, sample adequacy, final pathologic...
Purpose The application of histotripsy, an emerging noninvasive, non-ionizing, and non-thermal tumor treatment, is currently limited by the inherent limitations diagnostic ultrasound as sole targeting modality. This study evaluates feasibility accuracy cone beam computed tomography (CBCT) guidance for histotripsy treatments in vivo porcine model.
The goal of this study was to compare the outcome, complications, and charges percutaneous renal cryoablation laparoscopic solid masses.A total 30 cryoablations (mean tumor size, 2.1 cm) in patients age, 67.0 years) 60 2.5 46 67.4 were compared. size tumor, procedural hospital charges, length stay, follow-up parameters recorded. Monitoring after ablation performed every 3 months using contrast-enhanced MRI or CT.Both masses had a high technical success rate (30/30 [100%] 59/60 [98.3%])....
To evaluate computed tomographic (CT) colonography performance and program outcome measures in an older cohort (65-79 years) of established large-scale colorectal cancer screening program.This HIPAA-compliant study was approved by the institutional review board; informed consent waived. Retrospective analysis 65-79-year-old (n = 577) from University Wisconsin CT 5176) undertaken. Performance including advanced neoplasia prevalence colonoscopy referral, extracolonic finding, work-up,...