A5003207007- Stress Responses and Cortisol
- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Exercise and Physiological Responses
- Adipose Tissue and Metabolism
- Virology and Viral Diseases
- Travel-related health issues
- Psychedelics and Drug Studies
- Vaccine Coverage and Hesitancy
- War, Ethics, and Justification
- Environmental Toxicology and Ecotoxicology
- American Constitutional Law and Politics
- Water Quality and Pollution Assessment
- Neuroendocrine regulation and behavior
- Urban, Neighborhood, and Segregation Studies
- Behavioral Health and Interventions
- Neurotransmitter Receptor Influence on Behavior
- Transcranial Magnetic Stimulation Studies
- Gender, Security, and Conflict
- Thermoregulation and physiological responses
- Sports Performance and Training
- Sex and Gender in Healthcare
- Circadian rhythm and melatonin
- Stroke Rehabilitation and Recovery
- Nicotinic Acetylcholine Receptors Study
University of Colorado Denver
2018-2024
University of Denver
2019
Common stress-related mental health disorders affect women more than men. Physical activity can provide protection against the development of future (i.e. stress resistance) in both sexes, but whether there are sex differences exercise-induced resistance is unknown. We have previously observed that voluntary wheel running (VWR) protects female and male rats anxiety- exaggerated fear-like behavioral effects inescapable stress, time-course magnitude VWR-induced resilience has not been compared...
The largest measles outbreak in the United States during 1999 was traced to a 34-year-old minister with an undocumented history of vaccination, infected while traveling outside States. Local health departments Central Virginia Health District performed epidemiological and laboratory investigation that identified 14 additional confirmed cases measles, including 2 care providers 5 congregation members. Eight (53%) occurred among adults aged 30-35 years 7 (47%) children 13 months 8 years....
Abstract Systemic manipulations that enhance dopamine (DA) transmission around the time of fear extinction can strengthen and reduce conditioned relapse. Prior studies investigating brain regions where DA augments focus on targets mesolimbic mesocortical systems originating in ventral tegmental area, given role these neurons prediction error. The dorsal striatum (DS), a primary target nigrostriatal system substantia nigra (SN), is implicated behaviors beyond its canonical movement, such as...
Abstract Elevated ovarian hormones during fear extinction can enhance memory retention and reduce renewal, but the mechanisms remain unknown. Ovarian modulate dopamine (DA) transmission, a key player in extinction. In males, stimulation of substantia nigra (SN) DA neurons reduces renewal; an effect mimicked by D1 receptor agonist into dorsolateral striatum (DLS). The current studies tested role SN-DLS pathway estrous cycle-modulation relapse. cycling female, Long-Evans rats, proestrus or...
Common stress-related mental health disorders affect women more than men. Physical activity can provide protection against the development of future (i.e., stress resistance) in both sexes, but whether there are sex differences exercise-induced resistance is unknown. We have previously observed that voluntary wheel running (VWR) protects female and male rats anxiety- exaggerated fear-like behavioral effects inescapable stress, time-course magnitude VWR-induced resilience has not been...
The poor long‐term success of fear extinction‐based exposure therapy for post‐traumatic stress disorder (PTSD) is often caused by the relapse previously extinguished fear. We have observed that activation substantia nigra (SN) dopamine (DA) neurons during extinction enhances memory and reduces renewal. Although specific targets mediating effects SN DA on are unknown, their identification could pave way development novel strategies to reduce in PTSD patients. A primary target dorsal striatum,...
Exercise has beneficial effects on cognition and mental health, such as enhancing the extinction of a traumatic memory. Rats allowed to run in wheel for single, two‐hour session immediately following fear training show enhanced The mechanisms by which exercise augments are unknown. mammalian target rapamycin (mTOR) is translation regulator involved synaptic plasticity, cellular signals sensitive exercise. Chronic increases mTOR signaling brain regions learning, but whether single bout...