A5100387931- Quinazolinone synthesis and applications
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Cancer-related molecular mechanisms research
- Reproductive tract infections research
- Circular RNAs in diseases
- SARS-CoV-2 detection and testing
- Cytomegalovirus and herpesvirus research
- Synthesis and Biological Evaluation
- Insect and Pesticide Research
- Acute Myocardial Infarction Research
- MicroRNA in disease regulation
- Genetics and Neurodevelopmental Disorders
- Cancer Mechanisms and Therapy
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Insect Resistance and Genetics
- Facial Rejuvenation and Surgery Techniques
- Vitamin D Research Studies
- vaccines and immunoinformatics approaches
- SARS-CoV-2 and COVID-19 Research
- Genomics and Rare Diseases
- Maternal and fetal healthcare
- Biomedical Research and Pathophysiology
- Artificial Intelligence in Healthcare and Education
- Viral Infectious Diseases and Gene Expression in Insects
Xian Center for Disease Control and Prevention
2024
Guangzhou Medical University
2024
Beijing Institute of Technology
2021-2023
South China University of Technology
2023
Fuzhou Second Hospital
2023
Sichuan University
2023
Zhuhai Institute of Advanced Technology
2023
Xinqiao Hospital
2023
Second Affiliated Hospital of Xi'an Jiaotong University
2022-2023
Huazhong University of Science and Technology
2022
Background and Aims: Extrachromosomal circular DNAs (eccDNAs) are prevalent in cancer genomes emerge as a class of crucial yet less characterized oncogenic drivers. However, the structure, composition, genome-wide frequency, contribution eccDNAs HCC, one most fatal cancers, remain unexplored. In this study, we provide comprehensive characterization human HCC demonstrate an role microRNA (miRNA)-17-92-containing tumor progression. Approach Results: Using circle-sequencing method, identify...
The widespread and frequent use of antibiotics to treat diseases or encourage animal growth has resulted in their persistence accumulation water, soil, sediments. As a typical emerging pollutant the environment, have become an important research focus recent years. Antibiotics are commonly found at trace levels water environments. Unfortunately, determination various types antibiotics, all which exhibit different physicochemical properties, remains challenging endeavor. Thus, developing...
The Omicron EG.5 lineage of SARS-CoV-2 is currently on a trajectory to become the dominant strain. This phase 2 study aims evaluate immunogenicity SCTV01E-2, tetravalent protein vaccine, with specific emphasis its against EG.5, comparing it progenitor SCTV01E (NCT05933512). As 12 September 2023, 429 participants aged ≥18 years were randomized into groups (N = 215) and SCTV01E-2 214). Both vaccines showed increases in neutralizing antibody (nAb) 5.7-fold increase 9.0-fold 14 days...
As a proteoglycan, VCAN exists in the tumor microenvironment and regulates proliferation, invasion, metastasis, but its role hepatocellular carcinoma (HCC) has not yet been elucidated.To investigate expression potential mechanism of action HCC.Based on The Cancer Genome Atlas Liver Hepatocellular Carcinoma dataset, we explored correlation between clinical features, analyzed prognosis patients with high low expression. was by Gene Ontology analysis, Kyoto Encyclopedia Genes Genomes gene set...
Bioassays and binding tests between Cry toxins (CrylAa, CrylAb, CrylAc, Cry2Ab) brush-border membrane vesicles (BBMVs) from larvae of a Bacillus thurningiensis (Bt)-susceptible (96S) two CrylAc-resistant strains (BtR LFR10) were conducted for investigating cross-resistance to Cry2Ab in Helicoverpa armigera (Hiibner) (Lepidoptera: Noctuidae). The resistance ratio (RR) values the BtR LFR10 CrylAc 2,971- 1.1-fold 253- 1.0-fold, respectively, indicating that there was no Cry2Ab. experiments...
The Children Neuropsychological and Behavioral Scale-Revision 2016 (CNBS-R2016) is a widely used developmental assessment tool for children aged 0-6 years in China. communication warning behavior subscale of CNBS-R2016 to assess the symptoms autism spectrum disorder (ASD), its value >30 points indicates ASD based on CNBS-R2016. However, we observed that with relatively lower values were also diagnosed later clinical practice. Thus, this study aimed identify suitable cutoff screening...
The Omicron EG.5 lineage of SARS-CoV-2 is currently on a trajectory to become dominant strain. This phase 2 study aims evaluate the immunogenicity SCTV01E-2, tetravalent protein vaccine, with specific emphasis its effectiveness against EG.5, comparing it progenitor SCTV01E (NCT05933512). As September 12, 2023, 429 participants aged ≥18 years were randomized (N=215) or SCTV01E-2 (N=214) groups. Both vaccines showed increases in neutralizing antibody (nAb) 5.7-fold increase and 9.0-fold groups...
Abstract Nasolabial folds (NLFs) are the most pronounced sign of facial aging. This study explored efficacy and safety polycaprolactone gel in treating Chinese patients with moderate-to-severe NLFs. Patients NLF who wished to be treated by dermal fillers were recruited from three centers between July 2017 September 2019. The randomizing ratio was 1:1 group (polycaprolactone injection) or control (sodium hyaluronate injection). primary endpoint effectiveness rate Wrinkle Severity Rating Score...
BACKGROUND: Ginkgo Folium has a favorable effect on non-alcoholic fatty live disease (NAFLD), but its mechanism remains unclear. OBJECTIVE: The aim of this study is to reveal the underlying in treatment NAFLD. METHODS: Ingredients and ingredients-related genes were collected from TCMSP database SwissTargetPrediction website, respectively. Genecards was used obtain NAFLD-related genes. Next, protein-protein interaction network key ingredients-genes constructed via Cytoscape3.7.0. Based...
Curiosity, as the strong desire to acquire new information, plays a crucial role in human behaviors. While recent research has delved into effects, behavioral manifestations, and neural underpinnings of curiosity, absence standardized assessment tools for measuring curiosity may hinder advancements this field. Here, we translate different scales Chinese test each translated scale by examining its reliability structural validity. Our results show that scores derived from these have comparable...
Emergency care for patients with chest pain can be a challenge in remote areas. Digital communication technology has the potential to improve outcomes by allowing early diagnosis and faster treatment. The aim of present study was investigate whether implementation coordinated digital-assisted program (CDAP) Chinese hospitals reduce door-to-balloon (D2B) time percutaneous coronary intervention (PCI) acute China. From March December 2011, 609 (CDAP group) requiring an emergency response were...
We established a regional cooperative emergency care system of ST-elevation myocardial infarction patients based on the internet things. In this article, current status and problems patient have been studied key influence factors are found. As results, shorter time from symptom onset to reperfusion is achieved with improved outcomes for ST-segment elevation (STEMI). Primary percutaneous coronary intervention (PCI) in STEMI significantly reduces mortality morbidity, particularly when...
Bioassays and binding tests between Cry toxins (Cry1Aa, Cry1Ab, Cry1Ac, Cry2Ab) brush-border membrane vesicles (BBMVs) from larvae of a Bacillus thurningiensis (Bt)-susceptible (96S) two Cry1Ac-resistant strains (BtR LFR10) were conducted for investigating cross-resistance to Cry2Ab in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). The resistance ratio (RR) values the BtR LFR10 Cry1Ac 2,971- 1.1-fold 253- 1.0-fold, respectively, indicating that there was no Cry2Ab. experiments BBMVs...
In this article, the author analyzes some features of functioning social networks in context a pandemic using example China. Mainly based on foreign publications, it is shown how influence phenomenon infodemic health emergencies. This problem considered issue government regulation public opinion during pandemic. As an example, article cites state’s use WeChat and Weibo coronavirus situation. Special attention paid to analysis “duration” criterion process disseminating online opinions. The...
Abstract Background Postpartum hemorrhage (PPH) is a leading cause of maternal mortality and severe morbidity worldwide involves disseminated intravascular coagulation (DIC) secondary to massive blood loss. The abnormality in response trauma or infection latent that may aggravate PPH. Case presentation A 26-year-old puerpera with 39 weeks menolipsis case lacks amniotic fluid uterus was examined. During the cesarean section, patient presented fever she became DIC shock. low this PPH diagnosed...
1. The long noncoding RNA lncGLM is significantly differentially expressed in the livers of peak-laying hens compared with that pre-laying hens, but its potential biological role and expression regulation are unclear.2. To explore function lncGLM, single nucleotide polymorphism (SNP) detection association analysis were carried out Gushi×Anka F2 resource population.3. tissues spatiotemporal characteristics analysed by real-time quantitative PCR. effects 17β-oestradiol on through vitro vivo...
Objective To evaluate the innovative application of chalazion forceps in surgery eyelid full-thickness laceration,especially with palpebral laceration or parts tissue loss. Methods In laceration, clampping on wound. The clinical data were retrospectively analyzed. Results Of 40 cases patients lacerations,wounds fixed appropriately,there are stable pressure pad, good hemostasis, and protection surgery, surgical time was significantly shorter excellent results. After surgery,39 40cases (40...
Objective: This study aimed to evaluate the correlation between stress hyperglycemia and clinical outcomes after large vessel occlusion stroke (LVO) at 90 days. Methods: The RESCUE BT trial was a multicenter, randomized, double-blind, placebo-controlled trial, consisting of 948 patients from 55 centers in China. In this subgroup study, 542 consecutive with glucose or glycated hemoglobin values were included. Stress evaluated both as tri-categorical variable (≤1.07 vs 1.08-1.29 ≥1.30)...