- Analytical Methods in Pharmaceuticals
- Ion Channels and Receptors
- Biochemical Analysis and Sensing Techniques
- Drug Solubulity and Delivery Systems
- Gastrointestinal motility and disorders
- Analytical Chemistry and Chromatography
- Gut microbiota and health
- Hydrogels: synthesis, properties, applications
- Insect behavior and control techniques
- Advanced Drug Delivery Systems
- Diet and metabolism studies
- Advancements in Transdermal Drug Delivery
- Genetic Mapping and Diversity in Plants and Animals
- Plant Stress Responses and Tolerance
- Analytical Chemistry and Sensors
- Plant Micronutrient Interactions and Effects
- Heavy Metal Exposure and Toxicity
- Pharmacogenetics and Drug Metabolism
- Sentiment Analysis and Opinion Mining
- Surgical Simulation and Training
- Chromatography in Natural Products
- Insect Utilization and Effects
- Artificial Intelligence in Healthcare and Education
- Plant responses to elevated CO2
- Iron Metabolism and Disorders
National Agri-Food Biotechnology Institute
2021-2025
Vellore Institute of Technology University
2025
National Institute of Plant Genome Research
2025
Central Agricultural University
2025
Indian Institute of Vegetable Research
2025
Panjab University
1987-2024
Institute of Medical Sciences
2024
Indian Institute of Technology Bombay
2023
University Hospital of Geneva
1993
University of Geneva
1988-1990
Release of two very soluble beta adrenergic blockers namely: metoprolol tartrate and alprenolol HCl from cellulose matrices containing hydroxypropylcellulose (HPC) or sodium carboxymethylcellulose (Na CMC) methylcellulose (MC), MC + Na CMC HPC in different ratios was studied distilled water using USP dissolution apparatus 2. Increase the ratio total polymer to drug has decreased release rate a nonlinear manner. When only one (HPC used, profiles were first-order sigmoidal nature respectively....
The gut barrier - including tight junction proteins (TJPs) and mucus layers, is the first line of defense against physical, chemical or pathogenic incursions. This compromised in various health disorders. Capsaicin, a dietary agonist Transient receptor potential vanilloid 1 (TRPV1) channel, reported to alleviate complications obesity. While it well known improve energy expenditure metabolism, prevent dysbiosis, more local effects on host particularly system remain elusive. To investigate...
Blood lead level (BLL) is the primary biomarker for lead-exposure monitoring in occupationally exposed workers. We evaluated occupational (OE) impact on cardiopulmonary functions lead-acid battery recycling unit Seventy-six OE cases and 30 control subjects were enrolled questionnaire-based socio-demographic, dietary, tobacco usage, medical history data. Anthropometric measurements, systolic diastolic blood pressure (SBP DBP), pulmonary function tests performed. Venous was collected BLL,...
Cereal bran consumption improves gastrointestinal and metabolic health. Unprocessed cereal brans have a limited shelf-life contain anti-nutrient phytochemicals. In the present study, lipids antinutrients (flavonoids, tannin, polyphenol) were removed from finger millet, kodo millet rice using chemo-enzymatic processing. The thus-obtained modified (MCBs) evaluated for their potential in preventing high fat diet (HFD)-induced obesity. C57BL/6 mice fed HFD or supplemented with 10% w/w (mFMB),...
Antagonism of transient receptor potential vanniloid-1 (TRPV1) and desensitization ankyrin-1 (TRPA1) nociceptors alleviate inflammatory bowel diseases (IBD)-associated chronic pain. However, there is limited literature available about their role in regulating the mucosal layer, its interaction with host physiology, luminal microbial community. The present study focuses on effects' intra rectal administration capsazepine (modulator TRPA1/TRPV1 expressing peptidergic sensory neurons) colonic...
Short-chain fatty acids (SCFAs), metabolites of colonic bacterial fermentation complex carbohydrates, are closely related to the release gut hormones. In this study, we examined involvement transient receptor potential ankyrin 1 (TRPA1) in SCFA-induced increase intracellular calcium ([Ca2+ ]i ) and its impact on hormone secretion using naturally TRPA1 expressing intestinal secretin tumour cell-1 (STC-1) cell line. Individual SCFAs their physiological mix enhanced influx TRPA1-dependent...
A first work on rhodium-catalyzed para -selective C–H alkynylation has been reported and its mechanistic insights were gleaned from experimental computational studies.